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化学学报
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化学学报 ›› 1965, Vol. 31 ›› Issue (6): 518-520. 上一篇    下一篇

嘌呤化合物的薄层层析——Ⅰ.咖啡因、可可豆碱和茶碱的分离

李忠   

  1. 河南中医学院
  • 投稿日期:1964-09-15 发布日期:2013-06-03

THE THIN LAYER CHROMATOGRAPHY OF XANTHINE COMPOUNDS Ⅰ. CAFFEINE, THEOBROMINE AND THEOPHYLLINE

LI CHUNG   

  1. College of Chinese Medicine, Honan
  • Received:1964-09-15 Published:2013-06-03

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被引次数

1

嘌吟化合物类是重要的药物和生物代谢物质,在药物、毒理以及生化分析中,常需要分离和鉴定该类化合物的混合物。本文报告无粘合剂的氧化铝薄层层析法应用于嘌吟化合物的分离和鉴定。

The thin layer chromatography on basic alumina of activity III(160-180 mesh) without binder has been applied to the separation of caffeine, theobromine, and theophyllene.With n-butanol: isoamyl alcohol : hydrochloric acid: water (8:2:1:20) as developing agents, the Rf values found were 0.924, 0.581, and 0.0 for caffeine,theobromine, and theophylline respectively. The angle of inclination employed for development wa 15-20°.