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化学学报
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化学学报 ›› 1981, Vol. 39 ›› Issue (2): 159-163. 上一篇    下一篇

论文

抗癌植物大叶唐松草化学成分的研究——Ⅰ.唐松草新碱和N-去甲唐松草新碱

林隆泽1, 范芝芸1, 宋纯清1, 杜传芬2, 徐任生1   

  1. 1. 中国科学院上海药物研究所;
    2. 中国人民解放军195医院
  • 投稿日期:1979-03-23 发布日期:2013-06-03

CHEMICAL CONSTITUENTS OF THE ANTICANCER PLANT THALICTRUM FABERI ULBER.Ⅰ.THALIDASINE AND N-DESMETHYLTHALIDASINE

LIN LONG-ZE1, FAN ZHI-YUN1, SONG CHUN-QING1, DU CHUAN-FEN2, XU REN-SHENG1   

  1. Shanghai Institute of Materia Medica, Academia Sinica
  • Received:1979-03-23 Published:2013-06-03

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从唐松草属植物大叶唐松草(Thalictrum faberi Ulbr.)的根中分离鉴识了四种成分,为唐松草新碱(thalidasine,1)、N-去甲唐松草新碱(2)、小蘖碱和β-谷甾醇,2为新生物碱,1对动物肿瘤有抗癌活性。

The crude extract of the whole plant of Thalictrum faberi Ulbr.(Ranunculaceae) has shown some beneficial effects in clinical trials in Shanghai's Changning District Hospital for treatment of cancer of stomach,In this paper,we reported the study on the chemical constituents of the roots of the plant,Four compounds were isolated from its aqueous ethanol extract,By means of chemical and spectral analyses,they were identified as thalidasine (1),N-lesmethylthalidasine (2),berberine and β-sitosterol,respectively,