化学学报 ›› 1981, Vol. 39 ›› Issue (6): 541-545. 上一篇    下一篇

论文

昆虫保幼激素类似物——萜烯基硫醚类化合物的合成

刘孟英, 阎忠诚   

  1. 中国科学院动物研究所 北京
  • 投稿日期:1979-08-28 发布日期:2013-06-03

SYNTHESIS OF JUVENILE HORMONE ANALOGUES——TERPENOID THIOETHERS

LIU MENG-YING, YAN ZHONG-CHENG   

  1. Institute of Zoology, Academia Sinica, Beijing
  • Received:1979-08-28 Published:2013-06-03

利用香叶基氯、6,7-环氧香叶基氯与巯基乙酸酯类的缩合反应,制得了10个新的萜烯硫醚类化合物:6,10-二甲基3-硫杂十一碳5,9-双烯酸酯(3a,b,c,d,e)和6,10-二甲基9,10-环氧3-硫杂十一碳5-烯酸酯(4a,b,c,d,e).

10 new torpenoid thioethers,such as 6,1O-dimethyl 3-thia-undeoa-5,9-dienoio acid esters(8) and 6,1O-dimethyl 9,1O-epoxy-3-thia-6-undeoenoio acid esters(4) were synthesized by condensation of thioglycolio acid esters with geranyl chloride(1) or 6,7-epoaygeranyl chloride(2).Juvenile hormonal activities of the synthotio compounds to pupae of meal worm(Tenebrio molitor L.) were studied.It has been proved that the activities of the epoxy compounds(4) is higher than those of the olefinio compounds(8).Compounds of type 4 showed moderate morphogenetio effect to meal worm pupae at a dosage of 50 μg/pupa.