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化学学报
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化学学报 ›› 1982, Vol. 40 ›› Issue (6): 539-549. 上一篇    下一篇

论文

三尖杉属植物中几种生物碱的质谱裂解规律的研究

虞启涛, 马广恩, 黄知恒   

  1. 中国科学院上海药物研究所
  • 投稿日期:1980-12-12 发布日期:2013-06-03
  • 通讯作者: 虞启涛

STUDIES ON THE FRAGMENTATION MECHANISMS OF ALKALOIDS ISOLATED FROM CEPHALOTAXUS UNDER ELECTRON IMPACT

YU QI-TAO, MA GUANG-EN, HUANG ZHI-HENG   

  1. Shanghai Institute of Materia Medica, Academia Sinica
  • Received:1980-12-12 Published:2013-06-03

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被引次数

1

本文用高分辨质谱法研究了由三尖杉属植物分得的高刺桐碱类和三尖杉碱类的质谱裂解规律.高刺桐类生物碱的质谱中有三类特征性离子:(1)(M-15)离子;(2)C环的(RDA)及(RDA-H)反应产生的离子;(3)B环裂解的产物离子.三尖杉碱类化合物则依C环上双键位置的不同,经不同的中间离子,再重排得相应的质谱峰.阐明这两类生物碱的质谱裂解规律,将有助于同类型未知生物碱的结构推断.

The fragmentation mechanisms of a series of alkaloids isolated from Cephdlotaxus, which is used for the treatment of some kinds of cancer, have been proposed based on the data of high resolution mass spectrometry. These compounds (1~9),aooording to their molecular skeleton, are divided into homoerythrina and cephalotazine types.