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化学学报
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化学学报 ›› 1982, Vol. 40 ›› Issue (8): 737-746. 上一篇    下一篇

论文

苦玄参化学成分的研究——Ⅰ.苦玄参苷元Ⅰ的结构

成桂仁1, 金静兰1, 文永新1, 陈毓群2, 甘立宪2, 周维善2   

  1. 1. 广西植物研究所 桂林;
    2. 中国科学院上海有机化学研究所
  • 投稿日期:1981-05-02 发布日期:2013-06-03
  • 通讯作者: 周维善

STUDIES ON THE CONSTITUENTS OF PICRIA FEL-TARRAE LOUR Ⅰ. THE STRUCTURE OF PICFELTARRAEGENIN I

CHENG GUI-REN1, JIN JING-LAN1, WEN YONG-XIN1, CHEN YU-QUN2, GAN LI-XIAN2, ZHOU WEI-SHAN2   

  1. 1. Guangsi Institute of Botany, Guilin;
    2. Shanghai Institute of Organic Chemistry, Academia Sinica
  • Received:1981-05-02 Published:2013-06-03

PDF

797

被引次数

27

从玄参科的苦玄参植物中分出一系列苦味苷的苷元.苦玄参苷元Ⅰ(1)是其主要成分.通过1及其衍生物的Uv,IR,1HNMR,13CNMR及MS的谱学分析和若干化学反应确定1的结构为具有二氢呋喃酮边链的新型四环三萜.苦玄参苷经药理实验证明有抗癌活性.

A seriea of new aglycones has been isolated from Picriczfel-tarrae Lour. Picfeltarraogenin I(1) which is the major aglyoone of this plant, has a molecular formula of C30H4405 m. p. 209-210℃, [α] 18D+158.9°(c. 1.00, MeOH).The structure of 1 which was determined by means of spectral analysis(UV, IR, 1HNMR, 13C NMR and MS) and chemical reactions, was proves to be a new tetracyelie triterpenoid with a characteristic side chain of 3-2H]-furanone. Piofeltarraenins, the glycosides of piofeltarraegenins, were shown to possess significant antitumor activity.