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化学学报
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化学学报 ›› 1987, Vol. 45 ›› Issue (3): 249-255. 上一篇    下一篇

研究论文

毛冬青化学成分的研究II: 毛冬青皂苷甲的化学结构

秦国伟;陈政雄;徐任生;蒋仲芳;梁敬国   

  1. 中国科学院上海药物研究所;广州市医药工业研究所
  • 发布日期:1987-03-15

Studies on the chemical constituents of Ilex pubescens Hook et Am II: The structure of ilexsaponin A

QIN GUOWEI;CHEN ZHENGXIONG;XU RENSHENG;JIANG ZHONGFANG;LIANG JINGGUO   

  • Published:1987-03-15

PDF

528

被引次数

61

从毛冬青的根皮中分得一种新的三萜皂苷,命名为毛冬青皂苷甲,经^1H NMR、^1^3C NMR、MS、IR、UV和化学转化产物的研究,推定它为3β,19α-二羟基-乌索-12-烯-24,28-二羧酸-28-β-D-葡萄吡喃糖基酯.

关键词: 紫外分光光度法, 化学成分, 红外分光光度法, 皂角苷, 质谱法, 核磁共振谱法, 碳13核磁共振谱法, 吡喃糖, 葡萄糖, 毛冬青

A new saponin, named ilexsaponin A (I), was isolated from the roots of I. pubescens and its structure elucidation is reported. I, white needles, C36H56O11, m.p. 285-287?(decompn.), [a]D11 + 39.2? who has pos. to the Liebermann-Burchard test. By hydrolysis with 5% H2SO4-EtOH, I afforded glucose and saponin (II), C30H46O5, which was converted to several derivatives When I was hydrolyzed with 2% HCl-MeOH, 3 artifact sapogenins were formed, which were also converted to several derivatives The structure of I was shown to be 3b,19a-dihydroxy-urs-12-ene-24,28-dioic acid-28-b-D-glycopyranosyl ester by the above chem. conversions and spectral anal. of 13C NMR, 1H NMR, MS, IR and UV. II is a new 19a-hydroxyursane sapogenin.

Key words: ULTRAVIOLET SPECTROPHOTOMETRY, CHEMICAL COMPOSITION, INFRARED SPECTROPHOTOMETRY, SAPONINS, MASS SPECTROGRAPHY, NMR SPECTROMETRY, C13 NMR SPECTROMETRY, PYRANOSE, GLUCOSE, ILEX PUBESCENS

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