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化学学报
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化学学报 ›› 1990, Vol. 48 ›› Issue (8): 825-829. 上一篇    下一篇

研究论文

粘委陵菜中的鞣质成分的研究

黄青;张本;张洪岩;李超生;吕琳;野中源一郎;西 五无   

  1. 吉林省中医中药研究所;日本九州大学药学部
  • 发布日期:1990-08-15

Studies on constituents of tanin from potentilla viscose J. don

HUANG QING;ZHANG BEN;ZHANG HONGYAN;LI CHAOSHENG;LU LIN;YE ZHONGYUANYILANG;XI   

  • Published:1990-08-15

PDF

387

被引次数

9

从枯委陵菜(potenjtilla viscosa J.Don)根中分离出七个鞣质成分, 经波谱分析, 化学降解和衍生物制备等手段确定了它们的化学结构, 分别为(+)-儿茶素(1), (+)-儿茶素3-O-β-D葡萄糖苷(2), afzelechin-(4α-8)-儿茶素(3), 原花色苷元B-3(4), 原花色苷元B-33'-O-β-D-葡萄吡喃糖苷(5), 原花色苷元C-2(6)和枯委陵菜素(potentillanin)(7), 其中5和7是首次发现的天然化合物,化合物1及2具有保肝作用。

关键词: 化学成分, 分子结构, 碳13核磁共振谱法, 吡喃糖, 葡萄糖, 质子磁共振谱法, 糖苷, 蔷薇科, 化学降解, 单宁

Seven compounds were isolated from the root of P. viscosa J. Don, family Rosaceae. By means of [1H]NMR, [13C]NMR and mass spectral anal. and chem. studies, their chem. structures were elucidate to be (+)-catechin, (+)-catechin-3-O-b-D-glucoside (I), afzelechin(4a-8)-catechin, procyanidin B-3, procyanidin B-3 3'-O-b-D-glucopyranoside, procyanidin C-2, and potentillanin. I exhibited a protective effect against hepatitis symptoms in test animals.

Key words: CHEMICAL COMPOSITION, MOLECULAR STRUCTURE, C13 NMR SPECTROMETRY, PYRANOSE, GLUCOSE, PROTON MAGNETIC RESONANCE SPECTROMETRY, GLYCOSIDE, ROSACEAE, CHEMICAL DEGRADATION, TANNIN

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