化学学报 ›› 1995, Vol. 53 ›› Issue (12): 1209-1214. 上一篇    下一篇

研究论文

从D-甘露糖醇制备(R)和(S)-3,3-二甲基-2,3-O-异亚丙基甘油酸甲酯

许杏祥;谢煦   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1995-12-15

Synthesis of (R)-and(S)-3,3-dimethyl-2,3-O-iso-propylideneglycerinate from D-mannitol

XU XINGXIANG;XIE XU   

  • Published:1995-12-15

本文提出了一种由D-甘露糖醇出发合成一对高光学纯度的异亚丙基保护的3,3-二甲基甘油酸甲酯2a和2b的有效方法

关键词: 红外分光光度法, 质谱法, 核磁共振谱法, 甘露糖醇, 甘油酸甲酯

(R)-and(S)-3,3-dimethyl-2,3-O-iso-propylideneglycerinate 2a and 2b used as building blocks for the synthesis of Yingzhaosu B respectively, were synthesized from D-mannitol in a new approach. The enantiomeric purity was determined using a chiral NMR shift reagent and preparing into Mosher ester.

Key words: INFRARED SPECTROPHOTOMETRY, MASS SPECTROGRAPHY, NMR SPECTROMETRY, MANNITE (=MANNITOL), METHYL GLYCERATE

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