全二维气相色谱/飞行时间质谱用于卷烟主流烟气中酚类化合物的表征

化学学报 ›› 2004, Vol. 62 ›› Issue (8): 804-810. 上一篇下一篇

研究论文

全二维气相色谱/飞行时间质谱用于卷烟主流烟气中酚类化合物的表征

路鑫¹, 蔡君兰², 武建芳¹, 孔宏伟¹, 赵明月², 花瑞香¹, 刘建福³, 许国旺¹

1. 中国科学院大连化学物理研究所, 国家色谱研究分析中心, 大连, 116011;
2. 中国烟草总公司郑州烟草研究院, 郑州, 450000;
3. 长沙卷烟厂, 长沙, 410000

投稿日期:2003-07-04 修回日期:2003-12-28 发布日期:2014-02-18
通讯作者: 许国旺,E-mail:dicp402@mail.dlptt.ln.cn E-mail:dicp402@mail.dlptt.ln.cn
基金资助:
国家自然科学基金(No.20175028)和中国烟草专卖局科研基金资助项目.

Characterization of Phenols in Cigarette Mainstream Smoke Condensate by Using Comprehensive Two-dimensional Gas Chromatography/Time-of-flight Mass Spectrometry

LU Xin¹, CAI Jun-Lan², WU Jian-Fang¹, KONG Hong-Wei¹, ZHAO Ming-Yue², HUA Rui-Xiang¹, LIU Jian-Fu³, XU Guo-Wang¹

1. National Chromatographic Research and Analysis Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116011;
2. Chemistry Department, Zhengzhou Tobacco Research Institute of China National Tobacco Corporation, Zhengzhou 450000;
3. Changsha Tobacco Factory, Changsha 410000

Received:2003-07-04 Revised:2003-12-28 Published:2014-02-18

文章分享

摘要/Abstract

建立了卷烟主流烟气粒相物中酚类化合物组成研究的全二维气相色谱/飞行时间质谱方法,并用所建立的方法对一种市售混合型卷烟主流烟气粒相物中的酚类馏分组成进行了表征.采用TOFMS谱图库检索辅以二维"结构谱图"的定性手段,初步鉴定出了其中250个酚类化合物.这些酚类化合物包括66个烷基苯酚、47个烯基苯酚、57个萘酚、17个苯基苯酚、32个甲氧基苯酚、9个酚酮和15个酚醛化合物.同时对不同类型的酚类化合物在二维气相色谱上的分布模式进行了讨论.

关键词: 卷烟主流烟气粒相物, 酚类化合物, 全二维气相色谱/飞行时间质谱(GC×GC/TOFMS)

A comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry (GC×GC/TOFMS) method has been developed for the characterization of phenols in mainstream cigarette smoke condensate. A commercially available blend type cigarette has been investigated by using the developed method. Auto data processing by TOFMS software combined with "structured chromatogram" was used to assign the components. 250 phenols were tentatively identified including 66 alkylphenol derivatives, 47 alkenylphenol derivatives, 57 naphthalenol derivatives, 17 phenylphenol derivatives, 32 methoxyphenol derivatives, 9 acylphenol derivatives and 15 hydroxybenzaldehyde derivatives. The distributing profiles of different phenol derivatives in two-dimensional chromatogram were discussed.

Key words: cigarette mainstream smoke condensate, phenol, comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry(GC×GC/TOFMS)

引用此文

路鑫, 蔡君兰, 武建芳, 孔宏伟, 赵明月, 花瑞香, 刘建福, 许国旺. 全二维气相色谱/飞行时间质谱用于卷烟主流烟气中酚类化合物的表征[J]. 化学学报, 2004, 62(8): 804-810.

LU Xin, CAI Jun-Lan, WU Jian-Fang, KONG Hong-Wei, ZHAO Ming-Yue, HUA Rui-Xiang, LIU Jian-Fu, XU Guo-Wang. Characterization of Phenols in Cigarette Mainstream Smoke Condensate by Using Comprehensive Two-dimensional Gas Chromatography/Time-of-flight Mass Spectrometry[J]. Acta Chimica Sinica, 2004, 62(8): 804-810.

导出引用 EndNote|Reference Manager|ProCite|BibTeX|RefWorks

分享此文

参考文献

[1] Dube, M. F.; Green, C. R. Rec. Adv. Tob. Sci. 1982, 8, 42.
[2] Mirvish, S. S.; Weisenburger, D. D.; Hinrichs, S. H.; Nickols, J.; Hinman, C. Carcinogenesis 1994, 15, 883.
[3] Melikian, A. A.; Hecht, S. S.; Hoffmann, D. Prog. Clin. Biol. Res. 1989, 298, 331.
[4] Forehand, J. B.; Dooly, G. L.; Moldoveanu, S. C. J. Chromatogr. A 2000, 898, 111.
[5] Zhao, M.-Y.; Zhou, F.-C. Acta Tabacaria Sinica 1992, 1, 1 (in Chinese).(赵明月, 周富臣, 中国烟草学报, 1992, 1, 1.)
[6] Risner, C. H.; Cash, S. H. J. Chromatogr. Sci. 1990, 28, 239.
[7] Snook, M. E.; Fortson, P. J.; Chortyk, O. T. Tob. Int. 1980, 182, 78.
[8] Liu, Z.; Sirimanne, S. R.; Patterson, D. G. J.; Needham, L. L. Anal. Chem. 1994, 66, 3086.
[9] Xu, G.-W.; Ye, F.; Kong, H.-W.; Lu, X.; Zhao, X.-J. Chin. J. Chromatogr. 2001, 19, 132 (in Chinese).(许国旺, 叶芬, 孔宏伟, 路鑫, 赵欣捷, 色谱, 2001, 19, 132.)
[10] Blomberg, J.; Schoenmakers, P. J.; Beens, J.; Tijssen, R. J. High Resol. Chromatogr. 1997, 20, 539.
[11] de Boer, J.; de Geus, H. J.; Brinkman, U. A. Environ. Sci. Technol. 1997, 31, 876.
[12] Phillips, J. B.; Beens, J. J. Chromatogr. A 1999, 856, 331.
[13] Dallüge, J.; Vreuls, R. J. J.; Beens, J.; Brinkman, U. A. T. J. Sep. Sci. 2002, 25, 201.
[14] Dallüge, J.; van Stee, L. L.; Xu, X.; Williams, J.; Beens, J.; Vreuls, R. J.; Brinkman, U. A. J. Chromatogr. A 2002, 974, 169.
[15] Dallüge, J.; van Rijn, M.; Beens, J.; Vreuls, R. J.; Brinkman, U. A. J. Chromatogr. A 2002, 965, 207.
[16] Korytar, P.; van Stee, L. L.; Leonards, P. E.; de Boer, J.; Brinkman, U. A. J. Chromatogr. A 2003, 994, 179.
[17] Ruan, C. H.; Xu, G. W.; Lu, X.; Hua, R. X.; Kong, H. W.; Xiao, K.; Yang, Q. Chromatographia 2003, 57 (Suppl.), S-265.
[18] Shellie, R.; Marriott, P. J.; Morrison, P. Anal. Chem. 2001, 73, 1336.
[19] Ledford, E. B.; Phillips, J. B. US 6007602, 1999.

全二维气相色谱/飞行时间质谱用于卷烟主流烟气中酚类化合物的表征

Characterization of Phenols in Cigarette Mainstream Smoke Condensate by Using Comprehensive Two-dimensional Gas Chromatography/Time-of-flight Mass Spectrometry

PDF

可视化

被引次数

摘要/Abstract

引用此文

分享此文

参考文献

相关文章 1

编辑推荐

相关统计

本文评价