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化学学报
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化学学报 ›› 2010, Vol. 68 ›› Issue (16): 1623-1628. 上一篇    下一篇

研究论文

双官能Fe3O4/CdSe/CdS荧光磁性复合物的制备和表征

黄孟琼，王秀玲，刘勇健   

  1. (苏州科技学院 化学与生物工程学院 苏州 215011)
  • 投稿日期:2010-01-04 修回日期:2010-03-14 发布日期:2010-04-20
  • 通讯作者: 黄孟琼 E-mail:szkj2009@163.com
  • 基金资助:

    量子点的合成及用于化妆品中有害物质的检测;顺序注册在线光催化分析系统研究;顺序注射生物传感器在线监控基因重组发酵过程

Synthesis and Characterization of Bifunctional Fe3O4/CdSe/CdS Fluorescent Magnetic Nanocomposites

HUANG Meng-Qiong, WANG Xiu-Ling, LIU Yong-Jian   

  1. (Department of Chemical and Biological Engineering, Suzhou University of Science and Technology, Suzhou 215011)
  • Received:2010-01-04 Revised:2010-03-14 Published:2010-04-20

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采用化学共沉淀法, 以FeCl2•4H2O和FeC13•6H2O为原料制备磁性Fe3O4纳米颗粒(MNPs), 采用氨基酸对其进行修饰使其表面连上氨基. 用巯基乙酸作为稳定剂合成了水溶性的CdSe/CdS量子点, 并利用偶联剂1-乙基-3-(3-二氨丙基)碳二亚胺盐酸盐(EDC)和N-羟基琥珀酰亚胺(NHS)连接氨基修饰的Fe3O4和带有羧基的CdSe/CdS, 成功制备了Fe3O4/CdSe/CdS荧光磁性纳米颗粒. 该荧光磁性纳米复合物保留了CdSe/CdS量子点优异的荧光特性, 平均粒径在40 nm左右; 磁化曲线表明此纳米复合物具有超顺磁性. 这种双官能复合纳米颗粒有望成为新型荧光磁性双标记复合微粒而广泛应用于免疫检测、荧光追踪、磁性分离等领域.

关键词: 双官能纳米结构, 量子点, 磁性颗粒

In this study, the preparation of a new kind of magnetic and luminescent Fe3O4/CdSe/CdS nanocomposites was demonstrated. Superparamagnetic Fe3O4 nanoparticles were first synthesized by hydrothermal coprecipitation of ferric and ferrous ions, followed by the modification of their surfaces with L-aspartic acid. The surface-modified Fe3O4 nanoparticles were then linked to CdSe/CdS quantum dots (QDs), which were modified with mercaptoacetic acid, to form the Fe3O4/CdSe/CdS fluorescent magnetic nanocomposites through the coordination of the amino groups on the surfaces of Fe3O4 and the carboxyl groups on CdSe/CdS QDs in the presence of 1-ethyl-3-(3-dimethylaaminopropyl) carbodilnide hydrochloride (EDC) and N-Hydroxysuccinimide (NHS). The structure and properties of as-synthesized nanocomposites were characterized by XRD, EDS, TEM, Vibrating sample magnetometer (VSM) and photoluminescence (PL). It was indicated that the nanocomposites have a typical diameter of 40 nm and possess not only magnetic properties but also photoluminescence properties. The synthesized bifunctional nanocomposites could be used in a variety of bioanalytical assays such as luminescence detection, magnetic separation, drug delivery, biotechnology/biomedicine and so on.

Key words: bifunctional nanostructures, quantum dots, magnetic nanoparticles