化学学报 ›› 2010, Vol. 68 ›› Issue (21): 2227-2230. 上一篇    下一篇

研究论文

大红袍中两个新的双氢异黄酮类化合物

张盛1,谭青1,寿清耀1,秦国伟*,2,沈征武*,1,3   

  1. (1上海中医药大学中药学院 上海 201203)
    (2中国科学院上海药物研究所 上海 201203)
    (3巴塞利亚药业中国有限公司 海门 226100)
  • 投稿日期:2010-02-22 修回日期:2010-05-31 发布日期:2010-07-14
  • 通讯作者: 沈征武 E-mail:jeff_shen_1999@yahoo.com

Two New Isoflavonones from Radix Campylotropis hirtella

Zhang Sheng1 Tan Qing1 Shou Qingyao1 Qin Guowei*,2 Shen Zhengwu*,1,3   

  1. (1 School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203)
    (2 Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203)
    (3 Basilea Pharmaceutica China Ltd, Haimen 226100)
  • Received:2010-02-22 Revised:2010-05-31 Published:2010-07-14

传统中药大红袍通过各种色谱方法分离纯化, 得到两个新的双氢异黄酮类化合物, 根据其理化性质和光谱数据鉴定其结构分别为: 3 -香叶基-3,5,7,2 ,4 -五羟基-二氢异黄酮, 3(R)-2 -甲氧基-5,7,4 -三羟基-(3-甲基丁二烯)-二氢异黄酮.

关键词: 大红袍, 化学成分, 双氢异黄酮

Two new isoflavonones were isolated from Radix Campylotropis hirtella using column chromatography and their chemical structures were identified as 3 -geranyl-3,5,7,2 ,4 -pentahydroxyflavonol, 3(R)-2 -methoxyl-5,7,4 -trihydroxy-6-(3-methylbut-2-enyl)-isoflavanone.

Key words: Radix Campylotropis hirtella, chemical constituents, isoflavonone