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化学学报
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化学学报 ›› 1990, Vol. 48 ›› Issue (10): 939-945.    下一篇

研究论文

有生物活性的稀土-腺苷三磷酸系列物的合成及其量子化学理论计算的研究

彭周人;李一志;王流芳   

  1. 兰州大学化学系
  • 发布日期:1990-10-15

Studies on the synthesis and quantum chemical calculation of RE(III)-ATP series possessing biological activities

PENG ZHOUREN;LI YIZHI;WANG LIUFANG   

  • Published:1990-10-15

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552

被引次数

5 | 1

本文首次报道合成了稀土-腺苷三磷酸固态配合物RE(III)-ATP)RE=Y、La、Ce、Pr、Nd、Sm、Eu、Gd、Tb、Dy、Ho、Er、Tm、Yb、Lu)。运用红外、激光raman、热分析、紫外、顺磁、X射线衍射、元素分析、配位滴定等技术测定了上述配合物的化学组成和分子结构, 其分子式用通式表为[RE(III)(HATP)(H2O)4]。采用量子化学INDO方法计算了系列物的电子结构, 依据计算结果讨论了生物化学中高能磷酸键的本质。

关键词: 紫外分光光度法, 生物活性, 红外分光光度法, 热分析, 元素分析, 分子结构, Ｘ射线衍射分析, 量子化学, 腺嘌呤核苷三磷酸, 顺磁共振

Solid RE(III)-ATP complexes [RE = Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu] were synthesized and characterized through IR, laser-Raman, TGA, UV-visible, ESR, x-ray, elemental anal., complexometric titration and other experiments as RE(HL)(H2O)4 (H4L = ATP). The electronic structure of the series were calculated by INDO and the nature of high energy P-O bond in biol. chem. is discussed.

Key words: ULTRAVIOLET SPECTROPHOTOMETRY, BIOLOGICAL ACTIVITY, INFRARED SPECTROPHOTOMETRY, THERMAL ANALYSIS, ELEMENTAL ANALYSIS, MOLECULAR STRUCTURE, X-RAY DIFFRACTION ANALYSIS, QUANTUM CHEMISTRY, ADENOSINE TRIPHOSPHATE, PARAMAGNETIC RESONANCE

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