硅钨酸与盐酸巴马汀相互作用光谱研究及其分析应用

doi:10.6023/A1109301

化学学报 ›› 2012, Vol. 70 ›› Issue (06): 747-752.DOI: 10.6023/A1109301 上一篇下一篇

研究论文

硅钨酸与盐酸巴马汀相互作用光谱研究及其分析应用

李华春^a, 覃明丽^a,b, 谭克俊^a

a 发光与实时分析教育部重点实验室西南大学化学化工学院重庆 400715;
b 南充农产品质量监测检验中心南充 637000

投稿日期:2011-09-30 修回日期:2011-12-03 发布日期:2012-01-31
通讯作者: 谭克俊
基金资助:
国家自然科学基金(No. 20877063)和西南大学大型仪器设备开放基金(No. 201133)资助项目.

Study on Spectra of Interaction between Silicotungstic Acid and Palmatine Hydrochloride and Its Analysis Application

Li Huachun^a, Qin Mingli^a,b, Tan Kejun^a

a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715;
b Nanchong Municipal Monitoring and Testing Center for Agricultural Product Quality, Nanchong 637000

Received:2011-09-30 Revised:2011-12-03 Published:2012-01-31
Supported by:
Project was supported by the National Natural Science Foundation of China (No. 20877063) and the Large Instruments Open Foundation of Southwestern University (No. 201133).

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摘要/Abstract

在pH 为0.91 的HCl-NaOAc 缓冲介质中, 盐酸巴马汀与硅钨酸通过静电相互作用导致共振光散射信号显著增强,最大散射波长为297 nm, 增强的散射信号强度与盐酸巴马汀浓度在0.09～3.2 μg/mL 范围内呈线性关系, 据此建立了盐酸巴马汀的共振光散射分析方法, 检测限为9.1 ng/mL. 实验考察了pH、离子强度对体系的影响, 研究了体系紫外吸收光谱及荧光光谱, 讨论了共振光散射增强机理. 该方法用于黄藤素片、黄藤素胶囊及血清样品中盐酸巴马汀含量测定,RSD≤4.2%.

关键词: 共振光散射, 盐酸巴马汀, 硅钨酸

A novel resonance light scattering (RLS) method for the determination of palmatine hydrochloride (PaH) has been developed based on the largely enhanced RLS signals at 297 nm due to the interaction between Silicotungstic acid (STA) and PaH by electrostatic force in the pH 0.91 HCl-NaOAc medium. The linear range of PaH is 0.09～3.2 μg/mL. The limit of detection (LOD) is 9.1 ng/mL. In this work, the effects of pH and ionic strength on interaction were investigated. At the same time, the UV spectra, the fluorescence spectra and the reaction mechanism of system were also investigated. This method has been applied successfully for the determination of PaH in pharmaceutical and blood serum samples with RSD≤4.2%.

Key words: resonance light scattering, palmatine hydrochloride, silicotungstic acid

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李华春, 覃明丽, 谭克俊. 硅钨酸与盐酸巴马汀相互作用光谱研究及其分析应用[J]. 化学学报, 2012, 70(06): 747-752.

Li Huachun, Qin Mingli, Tan Kejun. Study on Spectra of Interaction between Silicotungstic Acid and Palmatine Hydrochloride and Its Analysis Application[J]. Acta Chimica Sinica, 2012, 70(06): 747-752.

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硅钨酸与盐酸巴马汀相互作用光谱研究及其分析应用

Study on Spectra of Interaction between Silicotungstic Acid and Palmatine Hydrochloride and Its Analysis Application

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