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化学学报
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化学学报 ›› 1959, Vol. 25 ›› Issue (1): 49-55. 上一篇    下一篇

论文

氨基糖的研究Ⅲ——6-O-(N’-乙酰-2’-胺基-2’-脱羟-β-D-葡萄糖甙基)-N-乙酰-2-胺基-2-脱羟-D-葡萄糖的合成

汪猷, 戴行义   

  1. 中国科学院有机化学研究所
  • 投稿日期:1958-10-06 发布日期:2013-06-03

AMINO SUGARS——Ⅲ SYNTHESIS OF 6-0-(2’-N’-ACETAMIDO-2’-DEOXY-β-D-GLUCOSYL)-2-ACETAMIDO-2-DEOXY-D-GLUCOSE

WANG YU, TAI HSING-I   

  1. Institute of Organic Chemistry, Academia Sinica
  • Received:1958-10-06 Published:2013-06-03

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作者用Knigs-Knorr的方法,从1,2,3,4-四乙酰-2-胺基-2-脱羟-β-D-葡萄糖和1-溴-2,3,4,6-四乙酰-2-胺基-2-脱羟-α-D-葡萄糖合成八乙酰异壳二糖,经氨解得二乙酰异壳二糖([6-O-N'-乙酰-2'-胺基-2'-脱羟-β-D-葡萄糖甙基]-N-乙酰-2-胺基-2-脱羟-D-葡萄糖)。

For the synthesis of 6-0-(2'-acetamido-2，一deozy-,B-D-glucosyl)-2-acetamido-2-deogy-D-glucose (or 2, 2'-diacetyl-iso-chitobiose) (VII), crystalline 1, 2, 3, 4-totraacetyl-2-amino-2-deozy-R-D=glucose (Ⅳ)[7] was shaken with a dry chloroform solution of freshly prepared 1-bromo-2,3,4,6-tetraacetyl-2-amino-2-deozy-β-D-glucose,using anhydrous calcium sulphate as dessicant[4] and silver ozide as condensing agent.