化学学报 ›› 1957, Vol. 23 ›› Issue (6): 455-461. 上一篇    下一篇

论文

二氮六圜衍生物Ⅱ.1-甲基-4-烃氧基苯氨基硫代甲酰二氮六圜鹽酸鹽及脂肪二元酰-二-(1-甲基二氮六圜)鹽酸鹽的合成

董永明, 宋鸿锵, 张其楷   

  1. 中国人民解放军医学科学院
  • 投稿日期:1957-05-31 发布日期:2013-06-03

PIPERAZINES Ⅱ. SYNTHESES OF THE HYDROCHLORIDES OF 1-METHYL-4-(ALKOXYPHENYL THIOCARBAMYL)-PIPERAZINES AND ALKYLENE DIACYL DI-(1-METHYL-PIPERAZIDES)

TUNG YEONG-MING, SOONG HONG-TSIANG, CHANG CHI-CHIEK   

  1. Institute of Medical Sciences
  • Received:1957-05-31 Published:2013-06-03

本文报告1-甲基-4-(烃氧基苯氨基硫代甲酰)二氮六圜鹽酸鹽及脂肪二元酰-二-(1-甲基二氮六圜)鹽酸鹽的合成。前者是將1-甲基二氮六圜和异硫氰酸烃氧基苯酯在乙醚中作用制取。后者系以1-甲基二氮六圜与相应的脂肪二元酰氯在苯液中作用而成。

Seven 1-methyl-4-(alkoxyphenyl thiocarbamyl)piperazinehydrochlorides and three alkylene diacyl-di-(1-methyl piperazide) hydrochlorides have been prepared for testing their activity against schistosomiasis in experimental animals,which were infected with Schistosoma Japonica.