化学学报 ›› 1955, Vol. 21 ›› Issue (1): 38-41. 上一篇    下一篇

论文

嘧啶的研究:4-甲基-5-乙基2, 6-二甲氧基嘧啶对硷的反应

纪育澧, 凌育宸   

  1. 中央卫生研究院药物学系
  • 投稿日期:1954-11-20 发布日期:2013-06-04

PYRIMIDINE RESEARCH:ACTION OF ALKALI ON 4-ME-THYL5-ETHYL-2, 6-DIMETHOXY-PYRlMIDlNE

CHl YUOH-FONG, LING YUOH-CHERN   

  1. Department of Therapeutics, Central Institute of Health
  • Received:1954-11-20 Published:2013-06-04

1.鹼作用於4-甲基-5-乙基-2,6-二甲氧基嘧啶,生成2-甲氧基-5-乙基-6-甲基-4-酮-3,4-二氫化嘧啶。2.乙醇氨作用於2-甲氧基-5-乙基-6-甲基-4-酮-3,4-二氫化嘧啶,生成2-氨基-5-乙基-6-甲基-4-酮-3,4-二氫化嘧啶。

The action of sodium methoxide on 4-methyl-5-ethyl-2,6-dimethoxy-pyrimidine in 90% methyl alcohol gave 3,4-dihydro-4-keto-2-methosy-5-ethyl-6-methyl-pyrimidine, melting at 209-210°.