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化学学报 >

2012 , Vol. 70 >Issue 12: 1332 - 1336

DOI: https://doi.org/10.6023/A1202221

研究论文

单液滴萃取衍生化技术用于烟气中小分子醛类物质的分析

  • 朱逢君 ,
  • 张菁 ,
  • 郑赛晶 ,
  • 刘百战 ,
  • 郭寅龙
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  • a 中国科学院上海有机化学研究所上海质谱中心上海 200032;
    b 上海烟草(集团)公司上海 200082

收稿日期: 2012-02-22

  修回日期: 2012-04-19

  网络出版日期: 2012-04-20

基金资助

国家自然科学基金(Nos. 20902104, 21072215, 21172250)资助项目

收起

Determination of Small Molecular Aldehydes in Cigarette Smoke by Extraction and Derivatization in Single Drop

  • Zhu Fengjun ,
  • Zhang Jing ,
  • Zheng Saijing ,
  • Liu Baizhan ,
  • Guo Yinlong
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  • a Shanghai Mass Spectrometry Center, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032;
    b Shanghai Tobacco Group Company, Shanghai 200082

Received date: 2012-02-22

  Revised date: 2012-04-19

  Online published: 2012-04-20

Supported by

Project supported by the National Natural Science Foundation of China (Nos. 20902104, 21072215, 21172250).

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摘要

本实验利用单液滴衍生化萃取技术(EDSD), 并与基质辅助激光解吸-傅立叶变换离子回旋共振质谱方法(MALDI-FTICR-MS)结合起来, 建立了一种用于分析烟气中小分子醛类物质的方法. 选择吉拉尔特试剂T作为衍生化试剂, 烟气中的小分子醛类物质可以形成季铵盐, 其在MALDI-FTMS中的灵敏度显著提高. 采用上述方法实现了对单口烟气中乙醛和丙烯醛的含量的分析. 该分析方法易于实现自动化, 为检测卷烟烟气中小分子醛类物质提供了一种简单、快速、准确的分析方法.

关键词： 单液滴衍生化萃取; 吉拉尔特试剂T; 烟气; 醛类; 定量

本文引用格式

朱逢君 , 张菁 , 郑赛晶 , 刘百战 , 郭寅龙 . 单液滴萃取衍生化技术用于烟气中小分子醛类物质的分析[J]. 化学学报, 2012 , 70(12) : 1332 -1336 . DOI: 10.6023/A1202221

Abstract

Extraction and derivatization in single drop (EDSD) coupled to matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI-FTICR-MS) was utilized to determine small molecular aldehydes in single puff smoke. Through employing Girard's reagent T as derivatization reagent, small molecular aldehydes (SMAs) transformed into quaternary ammonium salt, and the sensitivity of analysis for SMAs was significantly improved. Using this method, acetaldehyde and acrolein in single puff smoke were easily determined. This approach with an automatic potential provided a simple, rapid, and accurate procedure for the determination of SMAs in smoke.

Key words： extraction and derivatization in single drop; Girard’s reagent T; cigarette smoke; aldehyde; quantification

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