Acta Chimica Sinica ›› 1987, Vol. 45 ›› Issue (12): 1213-1216. Previous Articles     Next Articles

Original Articles

有机磷化合物的研究XXII: 亚甲基双(膦酸二烷基酯)及其衍生物

袁承业;丁贻祥   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1987-12-15

Studies on organophosphorus compounds XXII: [Methylene Bis-dialkylphosphonates and their derivatives

YUAN CHENGYE;DING YIXIANG   

  • Published:1987-12-15

A new facile synthetic method for the preparation of R2P(O)CH2P(O)(OEt)2 (I, R = EtO, BuO, Et, Ph) based on the phosphorylation of the carbanion derived from di-Et methylphosphonate was described. Alkylation of I gives, as expected, C-alkylation products from which substituted vinylphosphonate or phosphine oxide may result via the condensation of aldehyde or ketone. This is the first example utilizing the di-Et phosphoryl group as an electron-withdrawing function in a Horner-Emmons type reaction. It serves, therefore, as a one pot approach for the synthesis of phosphorus compounds with vinyl groups, potential intermediates for the preparation of various organophosphorus compounds

Key words: METHYLENE, INFRARED SPECTROPHOTOMETRY, ORGANO PHOSPHORUS COMPOUNDS, PHOSPHONIC ACID ESTER

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