Studies on the chemical constituents of antifertility plant gardenia jasminoides ellis I: The structure of gardenoic acid B, and early pregnancy terminating component

Acta Chimica Sinica ›› 1987, Vol. 45 ›› Issue (3): 301-304. Previous Articles Next Articles

Original Articles

抗生育植物栀子花化学成分的研究I: 抗早孕成分栀子花乙酸的结构

徐任生;秦国伟;朱大元;范芝芸;蒋福祥;张伯熙;王金成;王玉兰

中国科学院上海药物研究所;江西省庐山植物园

发布日期:1987-03-15

Studies on the chemical constituents of antifertility plant gardenia jasminoides ellis I: The structure of gardenoic acid B, and early pregnancy terminating component

XU RENSHENG;QIN GUOWEI;ZHU DAYUAN;FAN ZHIYUN;JIANG FUXIANG;ZHANG BOXI;WANG JINCHENG;WANG YULAN

Published:1987-03-15

Abstract

The flowers of G. jasminoides are used in Chinese folk medicine for birth control. EtOAc extract of the flowers showed significant effects on terminating early pregnancy in rats. Flash column chromatog. separation of the crude extract gave several components among which 2 new cycloartane triterpenoids, namely gardenic acid and gardenolic acid B (I) were active components. The structure of I, m.p. 214-216癈, [a]D17 + 51.2, C30H46O5, were deduced by spectral analyses on the acid and the diacetate II.

Key words: CHEMICAL COMPOSITION, INFRARED SPECTROPHOTOMETRY, C13 NMR SPECTROMETRY, PROTON MAGNETIC RESONANCE SPECTROMETRY, STRUCTURAL ANALYSIS, TRITERPENIC ACID, CONTRACEPTIVE, GARDENIA JASMINOIDES, GARDENOIC ACID B

CLC Number:

O629
R93

Cite this article

XU RENSHENG;QIN GUOWEI;ZHU DAYUAN;FAN ZHIYUN;JIANG FUXIANG;ZHANG BOXI;WANG JINCHENG;WANG YULAN. Studies on the chemical constituents of antifertility plant gardenia jasminoides ellis I: The structure of gardenoic acid B, and early pregnancy terminating component[J]. Acta Chimica Sinica, 1987, 45(3): 301-304.

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抗生育植物栀子花化学成分的研究I: 抗早孕成分栀子花乙酸的结构

Studies on the chemical constituents of antifertility plant gardenia jasminoides ellis I: The structure of gardenoic acid B, and early pregnancy terminating component

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