Electrochemical Depletion of Ascorbic Acid in the Detection of Hydrogen Peroxide--An Investigation Using SECM

Acta Chimica Sinica ›› 2004, Vol. 62 ›› Issue (14): 1339-1343. Previous Articles Next Articles

利用扫描电化学显微镜研究过氧化氢检测中电化学消除抗坏血酸

王康, 魏辉, 夏兴华

南京大学化学化工学院, 配位化学国家重点实验室, 分析科学研究所, 南京, 210093

投稿日期:2004-01-12 修回日期:2004-03-16 发布日期:2014-02-17
通讯作者: 夏兴华,E-mail:xhxia@nju.edu.cn E-mail:xhxia@nju.edu.cn
基金资助:
国家自然科学基金(No.20375016)与杰出青年科学基金(No.20125515)资助项目.

Electrochemical Depletion of Ascorbic Acid in the Detection of Hydrogen Peroxide--An Investigation Using SECM

WANG Kang, WEI Hui, XIA Xing-Hua

State Key Laboratory of Coordination Chemistry, Institute of Analytical Science, College of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093

Received:2004-01-12 Revised:2004-03-16 Published:2014-02-17

Abstract

An electrochemical method for detection of hydrogen peroxide has been advocated via selective elimination of interferences (i.e., ascorbic acid).In this method, the elimination of the interferences was achieved by positioning a tip electrode of scanning electrochemical microscopy (SECM) in the diffusion layer of an Au electrode and meanwhile applying a suitable potential on the substrate.Influence of the tip-substrate distance and the potentials of tip- and substrate-electrode on the selectivity and sensitivity of hydrogen peroxide detection was systematically investigated.Results showed that highly selective and sensitive detection of hydrogen peroxide free from interference of ascorbic acid (0.05 mmol·L^-1) could be obtained when the tip-substrate distance was 22.5 μm and the tip and substrate potentials were 0.5 and 0.4 V, respectively.The linear range for hydrogen peroxide detection is 4×10^-5～1×10^-3 mol·L^-1.Finally, potential application of the present method in fabrication of micro-electrochemical sensing devices has been discussed.

Key words: SECM, electrochemical depletion of interference, diffusion layer, ascorbic acid, hydrogen peroxide, electrochemical sensing micro device

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WANG Kang, WEI Hui, XIA Xing-Hua. Electrochemical Depletion of Ascorbic Acid in the Detection of Hydrogen Peroxide--An Investigation Using SECM[J]. Acta Chimica Sinica, 2004, 62(14): 1339-1343.

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利用扫描电化学显微镜研究过氧化氢检测中电化学消除抗坏血酸

Electrochemical Depletion of Ascorbic Acid in the Detection of Hydrogen Peroxide--An Investigation Using SECM

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