Acta Chimica Sinica ›› 2006, Vol. 64 ›› Issue (5): 435-438. Previous Articles     Next Articles

Original Articles

消旋卡多曲在空气中的热分解动力学

陶友田1, 占丹1, 张克立*,1,2   

  1. (1武汉大学化学与分子科学学院 武汉 430072)
    (2武汉大学纳米科学和技术研究中心 武汉 430072)
  • 投稿日期:2005-03-08 修回日期:2005-11-21 发布日期:2006-03-15
  • 通讯作者: 张克立

Kinetics of Thermal Decomposition of Racecadotril in Air

TAO You-Tian1, ZHAN Dan1, ZHANG Ke-Li*,1,2   

  1. (1 College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072)
    (2 Centre of Nanoscience and Nanotechnology Research, Wuhan University, Wuhan 430072)
  • Received:2005-03-08 Revised:2005-11-21 Published:2006-03-15
  • Contact: ZHANG Ke-Li

The thermal decomposition processes taking place in the solid-state racecadotril have been studied in air using TG-DTG/DTA and DSC techniques. TG-DTG/DTA and DSC curves showed that the decomposition proceeded through a well-defined step in air with the melting point of 77.4 ℃. The activation energies were calculated through the Friedman, Flynn-Wall-Ozawa and ASTM E698 methods, and the possible conversion functions were estimated through the multiple-linear regression method.

Key words: racecadotril, TG/DTG/DTA, differential scanning calorimetry, thermal decomposition, kinetics