Tuning Wavelength: Synthesis and Properties of 2-Substituted 8-Hydroxyquinoline Derivatives with Zinc(II) Complexes

Acta Chimica Sinica ›› 2008, Vol. 66 ›› Issue (4): 465-470. Previous Articles Next Articles

Original Articles

调控发光波长: 新型2-取代8-羟基喹啉衍生物金属锌配合物的合成与特性研究

张卫民, 曾和平*

(华南理工大学化学科学学院功能分子研究所广州 510641)

投稿日期:2007-06-30 修回日期:2007-09-10 发布日期:2008-02-28
通讯作者: 曾和平

Tuning Wavelength: Synthesis and Properties of 2-Substituted 8-Hydroxyquinoline Derivatives with Zinc(II) Complexes

ZHANG Wei-Min; ZENG He-Ping*

(Institute of Functional Molecule, School of Chemistry, South China University of Technology, Guangzhou 510641)

Received:2007-06-30 Revised:2007-09-10 Published:2008-02-28

Abstract

The 2-(2-(9H-fluoren-2-yl) vinyl)-8-hydroxyquinoline (6) and 2-(2-(phenanthren-9-yl) vinyl)-8-hydroxyquinoline (7) and their zinc complexes 8 and 9 have been synthesized. Compounds 6 and 7 were confirmed by UV-Vis, FT-IR, ESI-MS, ¹H NMR and elemental analysis. Regulation of the mesenchymal stem cells by compounds 6 and 7 have been evaluated by MTT assay, and the results show that these compounds have the ability to induce the proliferation of the mesenchymal stem cells. The zinc complexes were determined by FT-IR, FAB-MS and elemental analysis. Photoluminescence spectra show that the emission peaks of compounds 8 and 9 are at 602 and 628 nm, with yellow and red light emitted, respectively.

Key words: 8-hydroxyquinoline, mesenchymal stem cell, fluorescence spectra

Cite this article

ZHANG Wei-Min; ZENG He-Ping*. Tuning Wavelength: Synthesis and Properties of 2-Substituted 8-Hydroxyquinoline Derivatives with Zinc(II) Complexes[J]. Acta Chimica Sinica, 2008, 66(4): 465-470.

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调控发光波长: 新型2-取代8-羟基喹啉衍生物金属锌配合物的合成与特性研究

Tuning Wavelength: Synthesis and Properties of 2-Substituted 8-Hydroxyquinoline Derivatives with Zinc(II) Complexes

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