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Acta Chimica Sinica ›› 2003, Vol. 61 ›› Issue (3): 445-449. Previous Articles Next Articles
Original Articles
王明安;马祖超;路慧哲;王道全
发布日期:
Wang Mingan;Ma Zuchao;Lu Huizhe;Wang Daoquan
Published:
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The conformation of α,α-disubstituted Cyclododecanones have been studied by means of molecular dynamics computations, 1H NMR and X-ray diffraction analysis. The results indicate that their preferred conformation of ring skeleton is still [3333], with the carbonyl group present in the 2-C position. Both in the crystal and solution, the preferred conformation of α, α-disubstituted Cyclododecanones is α- corner- syn-, α-corner-oraft-disubstituted [3333]-2-one conformation. The first substituted group presents at α -corner- and position, while the second group is at α -corner- syn position.
Key words: cyclododecanone P, CONFORMATION, 1HNMR, XRD, MOLECULAR MECHANICS
CLC Number:
O621
Wang Mingan;Ma Zuchao;Lu Huizhe;Wang Daoquan. Conformation of α,α-Disubstituted Cyclododecanones[J]. Acta Chimica Sinica, 2003, 61(3): 445-449.
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