Acta Chimica Sinica ›› 2003, Vol. 61 ›› Issue (9): 1466-1470. Previous Articles     Next Articles

Original Articles

多组分光谱相关色谱及其在中药色谱指纺图谱分析中的应用

胡芸;梁逸曾;李博岩;徐承建;曾仲大   

  1. 中南大学化学化工学院中药现代化研究中心
  • 发布日期:2003-09-15

Multicomponent Spectral Correlative Chromatography Applied to Analysis of Chemical Fingerprints of Traditional Chinese Medicines

Hu Yun;Liang Yizeng;Li Boyan;Xu Chengjian;Zeng Zhongda   

  1. College of Chemistry and Chemical Engineering, Research Center of Modernization of Chinese Herbal Medicines, Central South University
  • Published:2003-09-15

Multicomponent spectral correlative chromatography is proposed based on orthogonal projection and correlative chromatography. In order to eliminate the influence of heteroscedastic noise derived from hyphenated instruments, the cosine value of between target component spectrum and its projected residue is applied as a criterion to test the correlative component chromatographic clusters of different chemical fingerprints of traditional Chinese medicines (TCMs). This method provides a practical tool for data processing, reasonable evaluation of chemical fingerprints of TCMs, and the basic theoretical research on relationship between the chemical fingerprints of TCM and its pharmaceutical efficacy.

Key words: CHINESE DRUG, CHROMATOGRAPHY, fingerprint of traditional

CLC Number: