The ternary complexes of copper(II) with amino acid (L-His and L-Lys) and nucleotide (5'-purine nucleotide and its salt of sodium) were first synthesized and characterized by elemental, conductivity, IR, ^1H NMR and ^1^3C NMR spectra. In the ternary complexes, the purine base coordinates with copper(II) through the 7-N atom. The phosphate group of 5'-nucleotide in the ternary complexes does not coordinate with copper(II). When the nucleotide takes part in the reaction in the form of Na2.5'-GMPH_2 and Na2.5'-GTPH_2, the phosphate group may be coordinate with copper(II) in the ternary complexes, but not for Na2.5'-IMPH_2.

Key words: AMINO ACID, INFRARED SPECTROPHOTOMETRY, ELEMENTAL ANALYSIS, NMR SPECTROMETRY, LYSINE, COPPER COMPLEX, TERNARY COMPLEX, HISTIDINE, NUCLEOTIDES