Studies on organo-silicon compounds with biological activity V: Synthesis of N-alkyl-N-trimethyl(triethoxy)silyl-2-furoic amides and biological activity

Acta Chimica Sinica ›› 1987, Vol. 45 ›› Issue (1): 87-91. Previous Articles Next Articles

Original Articles

具有生物活性的有机硅化合物的研究V: N-烃基-N-三甲(三乙氧)硅基-2-呋喃甲酰胺类化合物的合成及生物活性研究

廖仁安;李树正;张增佑;张素华;王明德;李秉武;谢庆兰

南开大学元素有机化学研究所

发布日期:1987-01-15

Studies on organo-silicon compounds with biological activity V: Synthesis of N-alkyl-N-trimethyl(triethoxy)silyl-2-furoic amides and biological activity

LIAO RENAN;LI SHUZHENG;ZHANG ZENGYOU;ZHANG SUHUA;WANG MINGDE;LI BIGWU;XIE QINGLAN

Published:1987-01-15

Abstract

Title compounds I (R1 = Pr, Bu, Me2CHCH2, Ph, 2-MeC6H4, 4-MeC6H4, 2-ClC6H4, 2,4-Cl2C6H3; R2 = Me, EtO) were prepared in 49-73% yield by treating amides II with ClSiR23. I showed fungicidal activity similar to that of carbendazol.

Key words: AMIDES, BIOLOGICAL ACTIVITY, SILOXANE, FUNGICIDES, STRUCTURE AND PROPERTY CORRELATION, ORGANO SILICON COMPOUNDS, FURANCARBOXYLIC ACID P

CLC Number:

O627

Cite this article

LIAO RENAN;LI SHUZHENG;ZHANG ZENGYOU;ZHANG SUHUA;WANG MINGDE;LI BIGWU;XIE QINGLAN. Studies on organo-silicon compounds with biological activity V: Synthesis of N-alkyl-N-trimethyl(triethoxy)silyl-2-furoic amides and biological activity[J]. Acta Chimica Sinica, 1987, 45(1): 87-91.

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具有生物活性的有机硅化合物的研究V: N-烃基-N-三甲(三乙氧)硅基-2-呋喃甲酰胺类化合物的合成及生物活性研究

Studies on organo-silicon compounds with biological activity V: Synthesis of N-alkyl-N-trimethyl(triethoxy)silyl-2-furoic amides and biological activity

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