A novel artificial receptor 1 for aromatic amino acid zwitterions was prepared in three steps from the chiral bis(aminomethyl) bicyclic guanidinium salt. The bicyclic guanidinium group is covalently connected with an azacrown ether and three naphthylmethyl group by means of chemically stable amide and imino bonds. The experiments of the competition extraction and ^1H NMR indicated that the receptor selectively binds to L-aromatic amino acid zwitterions and can transfer it from water into dichloromethane.

Key words: AMINO ACID, OLECULAR RECOGNITION, EXTRACTION, CROWN ETHER, PROTON MAGNETIC RESONANCE SPECTROMETRY