Triplet-state properties and photodynamic anti-cancer activities  of zinc octaalkoxy naphthalocynines

Acta Chimica Sinica ›› 2001, Vol. 59 ›› Issue (4): 619-622. Previous Articles

Original Articles

八烷氧基萘酞菁锌的激发三重态性质及光动力抗癌活性

吴谊群;陈耐生;黄金陵

黑龙江大学化学化工学院;福州大学化学系福州大学功能材料研究所

发布日期:2001-04-15

Triplet-state properties and photodynamic anti-cancer activities of zinc octaalkoxy naphthalocynines

Wu Yiqun;Chen Naisheng;Huang Jinling

Published:2001-04-15

Abstract

The triplet-state lifetime of a series of zinc octaalkoxy naphthalocynines ZnNc(OR)8(R=C4H9,C8H17,C12H25) were obtained by Laserflash photolysis. The abilities for photo-generating singlet oxygen and their photodynamic activities against HL60 cancer cell were investigated, and the photosensitization reaction mechanism of the title compounds as photosensitizers in photodynamic therapy was discussed.

Key words: NAPHTHALENE P, ALKOXYL GROUP, PHTHALOCYANIN (=PHTHALOCYANINE), EXCITED STATE, ANTINEOPLASTIC ACTIVITY, PHOTOSENSITIZATION

CLC Number:

O644

Cite this article

Wu Yiqun;Chen Naisheng;Huang Jinling. Triplet-state properties and photodynamic anti-cancer activities of zinc octaalkoxy naphthalocynines[J]. Acta Chimica Sinica, 2001, 59(4): 619-622.

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八烷氧基萘酞菁锌的激发三重态性质及光动力抗癌活性

Triplet-state properties and photodynamic anti-cancer activities of zinc octaalkoxy naphthalocynines

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