Cyclodextrin and polysaccharide derivatives that consist of glucopyranose units have been extensively used as chromatographic chiral stationary phases. The enantioseparations were examined using N-(3,5-dimethylphenyl)carbamates of glucose, galactose, mannose, xylose, maltose, sucrose, lactose and cellobiose as chiral selector bonded to silica gel via an arm in HPLC. Surprisingly, they also possess good enantioseparation selectivity, and there is a big chiral discriminating complementarity. This work indicates that oligosaccharides derivatives can soon become very attractive as a new kind of chiral stationary phase for HPLC.

Key words: N-(3,5-dimethylphenyl)carbamate of monosaccharide, N-(3,5-dimethylphenyl)carbamate of disaccharide, chiral stationary phase, HPLC