Acta Chimica Sinica ›› 1981, Vol. 39 ›› Issue (1): 83-89. Previous Articles     Next Articles

大叶桉酚甲的结构和合成

秦国伟, 陈政雄, 王洪诚, 钱名堃   

  1. 中国科学院上海药物研究所
  • 投稿日期:1979-01-05 发布日期:2013-06-03

THE STRUCTURE AND SYNTHESIS OF ROBUSTAOL A

QIN GUO-WEI, CHEN ZHENG-XIONG, WANG HONG-CHENG, QIAN MING-KUN   

  1. Shanghai Institute of Materia Medica, Academia Sinica
  • Received:1979-01-05 Published:2013-06-03

Robustaol A,a new acylph.lorogluoinol derivative,has been isolated from the leaves of medicinal plant Eucalyptus robusta Sm.(Myrtaoeae).The structure of robustaol A is proved to be 1 with the aid of UV,IR,NMR,MS spectral analyses,and through identification of its alkaline degradation products.The proposed structure of 1 has been confirmed by a four-step synthesis as shown in chart 2 of the Chinese text.Robustaol A showed antimalarial activity in mice.