A Convenient Method to Prepare Pyrano[2,3-d]pyrimidine Derivatives

doi:10.6023/cjoc201509037

Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (3): 659-663.DOI: 10.6023/cjoc201509037 Previous Articles Next Articles

Notes

一种构建吡喃并[2,3-d]嘧啶酮衍生物的简易方法

林志兰, 张俊民, 高原

深圳大学化学与环境工程学院深圳 518060

收稿日期:2015-09-28 修回日期:2015-10-26 发布日期:2015-11-06
通讯作者: 高原 E-mail:szgaoy311@163.com
基金资助:
国家自然科学基金(No. 21402124)资助项目.

A Convenient Method to Prepare Pyrano[2,3-d]pyrimidine Derivatives

Lin Zhilan, Zhang Junmin, Gao Yuan

College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060

Received:2015-09-28 Revised:2015-10-26 Published:2015-11-06
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21402124).

1. A Convenient Method to Prepare Pyrano[2,3-d]pyrimidine Derivatives.PDF(718KB)

Abstract

A series of pyrano[2,3-d]pyrimidine derivatives were synthesized by the reaction of 2-amino-3-cyano-4H-pyrans with acetic anhydride. This method has the advantages of short reaction times (10~15 min), simple operation and convenient post-treatment. All products were fully characterized by IR and ¹H NMR spectra. The molecular structures of 4a and 6a were confirmed using single-crystal X-ray analyses.

Key words: pyrano[2,3-d]pyrimidine derivatives, 2-amino-3-cyano-4H-pyran derivatives, acid catalysis

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Lin Zhilan, Zhang Junmin, Gao Yuan. A Convenient Method to Prepare Pyrano[2,3-d]pyrimidine Derivatives[J]. Chin. J. Org. Chem., 2016, 36(3): 659-663.

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一种构建吡喃并[2,3-d]嘧啶酮衍生物的简易方法

A Convenient Method to Prepare Pyrano[2,3-d]pyrimidine Derivatives

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