Cobalt-Catalyzed Asymmetric Hydroalkylation of Cyclopropenes

HIGHLIGHTS

何斌^a, 钮大文^a^,^b^,^*()

Bin He^a, Dawen Niu^a^,^b^,^*()

a West China Hospital, Sichuan University, Chengdu 610041
b School of Chemical Engineering, Sichuan University, Chengdu 610041

Bin He, Dawen Niu. Cobalt-Catalyzed Asymmetric Hydroalkylation of Cyclopropenes[J]. Chinese Journal of Organic Chemistry, 2021, 41(3): 1261-1263.

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Scheme 1. Bioactive molecules containing cyclopropane

Scheme 2. Cobalt-catalyzed asymmetric hydroalkylation of cyclopropenes

Scheme 3. Enantioselective and chemodivergent addition of cyclopropanols to oxabicyclic alkenes

Scheme 4. Representative examples of substrate

Scheme 5. Possible catalytic cycle

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