Study on ‌FeCl3-mediated Reaction of Aryl Boronic Esters with Electrophiles

doi:10.6023/cjoc202506018

Abstract

A concise approach to the synthesis of organoiron intermediate from organoboron and Fe(III) has been developed, and the reactivity of the intermediate with a series of electrophiles has been investigated. The results revealed that pinacol substituent of organoboron is crucial for C-B cleavage. The resulted organoiron intermediate is not stable, with weak nucleophicility. The coupling reactions of organoiron intermediate with acyl chlorides, anhydrides, isocyanates have been performed.

Key words: organoiron, organoboron, coupling, C-B cleavage

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Cui Lihua, Li Yatong, Wang Qifeng. Study on ‌FeCl₃-mediated Reaction of Aryl Boronic Esters with Electrophiles[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202506018.

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三氯化铁促进的芳基硼酸酯与亲电试剂的反应研究

Study on ‌FeCl₃-mediated Reaction of Aryl Boronic Esters with Electrophiles

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