Mn(OAc)3 promoted α-C-H Phosphonation of α-Oxo Ketene Dithioacetals with Dialkyl Phosphonates

doi:10.6023/cjoc202510001

Chinese Journal of Organic Chemistry

ARTICLE

Mn(OAc)₃促进α-羰基二硫缩烯酮与亚磷酸二烃酯的α-C-H膦酯化反应

于海丰^*, 孙雨瞳, 张绍洪, 李克, 赵晓波^*

白城师范学院化学学院吉林白城 137000

收稿日期:2025-10-04 修回日期:2025-11-18
基金资助:
吉林省自然基金(No. 20240101156JC)资助项目.

Mn(OAc)₃ promoted α-C-H Phosphonation of α-Oxo Ketene Dithioacetals with Dialkyl Phosphonates

Yu Haifeng^*, Sun Yutong, Zhang Shaohong, Li Ke, Zhao Xiaobo^*

College of Chemistry, Baicheng Normal University, Baicheng, Jilin 137000, China

Received:2025-10-04 Revised:2025-11-18
Contact: ^*E-mail: yuhf68105@sina.com; zhaoxiaobo@bcnu.edu.cn
Supported by:
Natural Science Foundation of Jilin Province, China (No. 20240101156JC).

Mn(OAc)₃ promoted α-C-H phosphonation of α-oxo ketene dithioacetals with dialkyl phosphonates for the synthesis of α-phosphonoketene dithioacetal derivates is developed. The reaction not only features mild reaction conditions, excellent yields and broad substrate scope but also enables gram-scale reaction, laying the foundation for further chemical transformations of α-phosphonoketene dithioacetal derivates.

Key words: Ketene dithioacetals, Dialkyl phosphonates, Manganese triacetate, Vinyl phosphonates

Cite this article

Yu Haifeng, Sun Yutong, Zhang Shaohong, Li Ke, Zhao Xiaobo. Mn(OAc)₃ promoted α-C-H Phosphonation of α-Oxo Ketene Dithioacetals with Dialkyl Phosphonates[J]. Chinese Journal of Organic Chemistry, doi: 10.6023/cjoc202510001.

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Mn(OAc)₃促进α-羰基二硫缩烯酮与亚磷酸二烃酯的α-C-H膦酯化反应

Mn(OAc)₃ promoted α-C-H Phosphonation of α-Oxo Ketene Dithioacetals with Dialkyl Phosphonates

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Mn(OAc)3促进α-羰基二硫缩烯酮与亚磷酸二烃酯的α-C-H膦酯化反应