Chinese Journal of Organic Chemistry 2026, 46(3)

- About the Cover:
  
  Recent advances in low-valent tungsten-catalyzed organic reactions are reviewed by Xu, Kong, Chen, Zhang, Ji, and Cheng on page 759. This review consolidates key developments in reaction design, mechanistic insights, and substrate scope expansion, positioning low-valent tungsten catalytic systems as a complementary and sus-tainable approach to conventional noble-metal systems
- About the Cover:
  
  The recent advances in the chiral synthesis of 2-aryl-2H- chromenes are summarized by Zhou, Liu, Lei, Yang, and Jiang on page 773. It highlights three principal strategies, including chemical resolution, kinetic resolution, and asymmetric catalysis enabled by chiral metal complexes or small organic molecules. Future perspectives for the development of this research field are also presented.
- About the Cover:
  
  A novel and efficient strategy for the synthesis of 2- hydroxy-indolin-3-ones through iodine-catalyzed intramolecular cyclization of N-(2-acetylphenyl)picolinade has been developed by He, Zhou, Jiang, Zhang, Wang, and Ma on page 961. This protocol features atom economy, metal-free, easy operation with cheap reagents, providing a useful and attractive route for the synthesis of 2-hydroxy-indolin-3-ones, which is widely presented in pharmaceuticals, biologically active molecules and natural products.
- About the Cover:
  
  The one-pot chemoselective methylation of carboxylic acids using N-methyl-N-nitrosourea (MNU) as diazomethane precursor is reported by Liu, Sun, Chu and coworkers on page 907. By means of in situ generating and consuming diazomethane, the efficient methylation of carboxylic acids has been realized via Na₂CO₃ promotion in dioxane/H₂O system, developing a safe and practical strategy for carboxylic acid methylation and phenyltetrazole N-methylation in pharmaceutical synthesis.
2026, 46(3)

25 March 2026
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REVIEWS ARTICLES HIGHLIGHTS

REVIEWS

Research Progress in Metal-Free Electrochemical C—H Bond Activation for the Construction of C—N/C—O Bonds

Hui Luo, Wenquan Wang, Yu He, Fuqiang Wang, Jinhui Yang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 697-724 DOI: 10.6023/cjoc202508020

Abstract( 108) HTML( 0) PDF(1315KB)( 67 )

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Research Progress in Synthesis of Indole Alkaloid Catharanthine

Xueqian Wang, Baozhong Duan, Hongchang Tian, Lei Zhang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 725-742 DOI: 10.6023/cjoc202509026

Abstract( 66) HTML( 1) PDF(1132KB)( 43 )

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Advances in Selective Oxidation of Carbohydrates

Qichang Yang, Xiaorui Zhang, Jian Lv, Shuang-Xi Gu

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 743-758 DOI: 10.6023/cjoc202508023

Abstract( 92) HTML( 1) PDF(938KB)( 34 )

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Recent Advances in Low-Valent Tungsten-Catalyzed Organic Reactions

Jialong Xu, Quan Kong, Jianhui Chen, Mingyue Zhang, Xiaoming Ji, Biao Cheng

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 759-772 DOI: 10.6023/cjoc202509012

Abstract( 90) HTML( 1) PDF(727KB)( 20 )

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Advances in Chiral Synthesis of 2-Aryl-2H-chromene Derivatives

Shunli Zhou, Ji Liu, Ting Lei, Binquan Yang, Shizhi Jiang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 773-785 DOI: 10.6023/cjoc202507004

Abstract( 111) HTML( 1) PDF(1205KB)( 114 )

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Recent Advances in Synthesis of Chiral Organoselenium Compounds

Yanhui Guo, Hongen Qu, Pei Liang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 786-805 DOI: 10.6023/cjoc202509022

Abstract( 106) HTML( 1) PDF(1067KB)( 52 )

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Transition Metal-Catalyzed Hydrosilylation and Boration of Methylenecyclopropanes

Jinyu Zhang, Zhigang Lu, Zhe Liu, Cong Wang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 806-816 DOI: 10.6023/cjoc202509017

Abstract( 46) HTML( 1) PDF(798KB)( 15 )

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Recent Advances on the Synthesis of Spirofluorene-Based Compounds

Cui Wei, Jinqiu Liu, Can Deng, Ning Zou, Wenjun Zhou

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 817-839 DOI: 10.6023/cjoc202507025

Abstract( 91) HTML( 1) PDF(1010KB)( 61 )

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Research Progress on Transition Metal-Catalyzed Carbosilylation of Alkenes

Meng Liu, Taobo Liu, Meilan Han, Shuyang Wang, Zhipaicuo Gui, Guangli Xu, Hongping Han

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 840-858 DOI: 10.6023/cjoc202507033

Abstract( 75) HTML( 1) PDF(826KB)( 58 )

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ARTICLES

Rhodium-Catalyzed Reduction of RS—SR to Thiophenols/Thiols with H₂

Xiaoxiang Xi, Ming Gao, Libiao Han

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 859-865 DOI: 10.6023/cjoc202509036

Abstract( 86) HTML( 1) PDF(683KB)( 21 )

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Near-Infrared Fluorescent Probe Based on Benzopyran Derivative for Highly Sensitive Detection of SO₂ Derivative and Bioimaging

Lin Liu, Lulu Zhou, Tianyu Liang, Keli Zhong, Xiaomei Yan, Lijun Tang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 866-871 DOI: 10.6023/cjoc202510002

Abstract( 101) HTML( 1) PDF(3303KB)( 33 )

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Synthesis and Biological Activity of Novel Pyrido[2,3-d]pyrimidine Containing Isoindolin-1-one

Ruixia Cao, Yuping Jia, Wenting Zhang, Shuwen Tan, Yaxin Xu, Shanshan Jiao, Xiaoxiao Li, Junhong Zhao

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 872-880 DOI: 10.6023/cjoc202510010

Abstract( 119) HTML( 1) PDF(545KB)( 45 )

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Study on Synthesis and H₂-Liberation Reaction of the Frustrated Lewis Pair (FLP)-Type Aluminum Hydrides

Yilin Chen, Chengjian Zhu

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 881-887 DOI: 10.6023/cjoc202510011

Abstract( 66) HTML( 1) PDF(1187KB)( 7 )

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Sub-stoichiometric Trifluoromethanesulfonic Anhydride/Dimethyl Sulfoxide-Mediated Cooxidation of Trivalent Phosphine to Tertiary Phosphine Oxides

Ming Li, Zhichao Wang, Dawei Shi, Fengkun Yang, Changcheng Wang, Bin Yang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 888-897 DOI: 10.6023/cjoc202510024

Abstract( 87) HTML( 1) PDF(557KB)( 42 )

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Ruthenium(II)-Catalyzed C7—H Monofluoroalkenylation of Indolines with gem-Difluorostyrenes

Lele Bai, Qingrong Wu, Zijuan Li, Xingwang Liu, Lu Deng, Qiuna Shen, Gaorong Wu

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 898-906 DOI: 10.6023/cjoc202510018

Abstract( 77) HTML( 1) PDF(602KB)( 15 )

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One-Pot Chemoselective Methylation Using N-Methyl-N-nitrosourea (MNU) as Diazomethane Precursor

Xuanyu Liu, Jiaxin Yao, Yuxiang Chen, Tianyu Zhang, Yuqing Jiang, Zhixue Hu, Hongshun Sun, Xueqiang Chu

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 907-914 DOI: 10.6023/cjoc202510007

Abstract( 129) HTML( 1) PDF(504KB)( 44 )

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A Green and Mild One-Pot Protocol for the Synthesis of 3-Iodo-/Bromo-imidazo[1,2-a]pyridines without Transition Metals

Liting Yang, Huiru Pan, Xiaoxu Xu, Yikai Zhang, Shuyu Lai, Xinyu Cao, Guoqun Liu, Huijie Qiao, Mingli Jiao

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 915-924 DOI: 10.6023/cjoc202509015

Abstract( 93) HTML( 1) PDF(611KB)( 49 )

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Mn(OAc)₃ Promoted α-C—H Phosphonation of α-Oxo Ketene Dithioacetals with Dialkyl Phosphonates

Haifeng Yu, Yutong Sun, Shaohong Zhang, Ke Li, Xiaobo Zhao

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 925-933 DOI: 10.6023/cjoc202510001

Abstract( 74) HTML( 1) PDF(644KB)( 20 )

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Synthesis of Aggregation-Induced Emission (AIE) Organic Polymorphs Based on Tetraphenylethene Structure: Research on Molecular Conformation and Detection Performance of Cys

Jidong Zhang, Hao Wang, Xiaoxin Quan, Shenghai Zhang, Wei She

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 934-940 DOI: 10.6023/cjoc202509019

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Study on Dearomatization [4＋2] Reactions of Allene Substrates

Yongzhen Qin, Yang Chen, Shuzhong He, Lan Yang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 941-950 DOI: 10.6023/cjoc202509001

Abstract( 86) HTML( 0) PDF(831KB)( 24 )

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A Catalyst and Solvent-Free Photochemical Acylation of N-Heteroarenes with Keto Acids

Xianting Huang, Xiaoqian Shen, Qingxu Wang, Zhongquan Liu

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 951-960 DOI: 10.6023/cjoc202509006

Abstract( 67) HTML( 0) PDF(1942KB)( 22 )

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Iodine-Catalyzed Intramolecular Cyclization for the Synthesis of 2-Hydroxy-indolin-3-ones

Yumeng He, Fengyuan Zhou, Nan Jiang, Yuqi Zhang, Jijiang Wang, Haojie Ma

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 961-967 DOI: 10.6023/cjoc202510019

Abstract( 61) HTML( 0) PDF(576KB)( 7 )

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A New β-Carboline and Its Analogues from Actinoalloteichus cyanogriseus OUCMDZ-413

Yukang Gao, Xiangui Mei, Yue Liu, Peng Fu, Peipei Liu, Weiming Zhu

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 968-973 DOI: 10.6023/cjoc202509027

Abstract( 68) HTML( 0) PDF(512KB)( 10 )

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An Oxidative Strategy for Generating Trichloromethyl Radical from Carbon Tetrahalides: Transition-Metal-Free Synthesis of Trichloromethylated Oxindoles

Ke Zhou, Zeyong Wang, Yalin Li, Qian Zhang, Xinyue Li, Hanfang Zou, Mingzhong Zhang, Shengrong Guo, Tieqiao Chen

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 974-985 DOI: 10.6023/cjoc202508011

Abstract( 103) HTML( 0) PDF(589KB)( 38 )

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Efficient Oxidation of Alcohols Using a Bioinspired Tetradentate Aminopyridine Manganese Catalyst with H₂O₂: Batch and Continuous Flow Studies

Chunnian Xia, Kailin Chen, Nuoqi Jin, Xinghui Nan, Bingyang Wang, Xinyi Wu, Qiangsheng Sun, Wei Sun

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 986-992 DOI: 10.6023/cjoc202508025

Abstract( 77) HTML( 0) PDF(454KB)( 23 )

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High-Throughput Screening of Ullmann Reaction Conditions and Study of Their Regularity

Zaixiang Guo, Yun Zou, Peihao Cheng, Fujun Li, Shengyang Tao

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 993-999 DOI: 10.6023/cjoc202507012

Abstract( 82) HTML( 0) PDF(6655KB)( 35 )

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Desulfinative Cross-Coupling of Aryl Sodium Sulfinate with Aryl Sulfonium Salts

Xinyu Liang, Chunchun Mi, Fujun Guo, Wenbin Xie, Qinqin Shi, Hui Huang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1000-1007 DOI: 10.6023/cjoc202509013

Abstract( 86) HTML( 0) PDF(481KB)( 48 )

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N-Heterocyclic Carbene (NHC)-Catalyzed [3＋2] Cycloaddition to Highly Diastereoselective Synthesis of Spirooxindole-Fused Cyclopentanes

Yuan Gao, Yan Liu, Shiwu Li, Tiansheng Tang, Yukun Meng, Zhifei Zhao

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1008-1016 DOI: 10.6023/cjoc202507009

Abstract( 76) HTML( 0) PDF(602KB)( 27 )

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Nickel-Catalyzed Annulation of Alkynyl with Trifluoroacetimidoyl Chlorides and H₂O: Facile Access to 2‑(Trifluoromethyl)indole Derivatives

Yu Sun, Yantao Zhu, Dong Zhang, Chunjie Ni

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1017-1026 DOI: 10.6023/cjoc202508002

Abstract( 67) HTML( 0) PDF(1835KB)( 24 )

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Magnesium-Promoted Selectively Reduction of Unprotected Indoles and Quinoxalines

Nana Wei, Wanzhen Guo, Xing Lu, Zhiqiang Ren, Haojie Ma, Yuqi Zhang, Jijiang Wang, Bo Han

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1027-1038 DOI: 10.6023/cjoc202508021

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Electrochemical Synthesis of 4-Sulfenylisocoumarins via Radical Cascade Annulation of o-Alkynylbenzoates with Thiophenols

Chao Ma, Xiaoling Xu, Xiang Luo, Ruijuan Lu, Guoqi Yu, Tao Cai

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1039-1049 DOI: 10.6023/cjoc202508022

Abstract( 71) HTML( 0) PDF(856KB)( 18 )

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Electrochemical Radical Dienylation Reaction of Arylphosphine Oxides

Xinyu Wang, Chenpei Huang, Chang Guo, Jin Song

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1050-1059 DOI: 10.6023/cjoc202509004

Abstract( 53) HTML( 0) PDF(534KB)( 14 )

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N-Bromosuccinimide-Promoted Direct Phosphorylation of Amines with P(O)—H Compounds

Qiaoli Li, Huabin Wang, Yan Qin, Jiamin Zhao, Fang Han, Xiongwei Liu, Bowen Pan, Qiang Huang, Ying Zhou

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1060-1069 DOI: 10.6023/cjoc202507034

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Phosphoric Acid-Catalyzed Double/Triple Pictet-Spengler Annulation/Oxidative Aromatization for Construction of C₂- and C₃-Symmetrical Quinazolinones

Zening Huang, Kaicheng Zuo, Tao Hu, Chengyang Zhang, Jinlong Zhang, Gaoxi Jiang

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1070-1077 DOI: 10.6023/cjoc202508003

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Terpenoids from the Leaves of Turpinia arguta and Their Bioactivities

Zhelu Jiang, Zeyu Zhao, Chunjing Chi, Jiangchuan Yu, Lihong Yan, Jinfeng Hu

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1087-1094 DOI: 10.6023/cjoc202507018

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A Bifunctional Triphenylamine-Based Fluorescent Dye for Anti-counterfeiting and Latent Fingerprint Detection

Chunlin Chen, Jie Tan, Bangcui Zhang, Guanchen Dong, Yanhua Yang, Xiangguang Li, Shulin Gao

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1095-1104 DOI: 10.6023/cjoc202507001

Abstract( 99) HTML( 1) PDF(3110KB)( 45 )

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HIGHLIGHTS

NiH-Catalyzed Asymmetric Hydrosulfinamidation of Aryl Alkenes

Yiming Hu, Xinjun Luan

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1105-1106 DOI: 10.6023/cjoc202600004

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Enantioconvergent Indole Alkylation Enabled by the Strategy of Borrowing Hydrogen

Yu Liu, Feng Shi

Chinese Journal of Organic Chemistry 2026, 46 (3), pp 1107-1109 DOI: 10.6023/cjoc202600005

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