Chin. J. Org. Chem. ›› 1999, Vol. 19 ›› Issue (1): 40-45. Previous Articles     Next Articles

Original Articles

取代α-苯基肉桂酸类化合物的合成及其光谱研究

何欣;牟丽媛;朱莉亚;林紫云;梁晓天   

  1. 中国医学科学院中国协和医科大学药物研究所
  • 发布日期:1999-02-25

Synthesis and spectroscopy study of α-phenylcinamic acids

He Xin;Mu Liyuan;Zhu Liya;Lin Ziyun;Liang Xiaotian   

  • Published:1999-02-25

Fourteen substituted α-phenylcinnamic acids were prepared by classical Perkin condensation reaction. The configuration of α- phenylcinnamic acids was determined by the NOE difference spectra. A plausible way of cleavage was involved in the formation of the specific fragment peaks in the MS of the α-phenylcinnamic acids. The characteristic chemical shift of the olefinic proton in ^1H NMR is also discussed.

Key words: BENZENE P, CINNAMIC ACID P, MASS SPECTROGRAPHY, CHEMICAL SHIFT, NMR SPECTROMETRY, SPECTROGRAPHIC ANALYSIS

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