A simple and efficient method for the synthesis of various substituted ureidoalkylphos-phonates was reported. α-(2- Thiazolylureido)-alkylphosphonic acid diphenyl esters(3) were synthesized by the reaction of (substituted) 2-amino (benzo) thiazole with α-isocyanatoalkylphosphonic acid diphenyl esters (2), which were prepared in one-pot by treating α-aminoalkylphosphonic acid diphenyl esters (1) with triphosgene. The yields of 3 are moderate to high (55.0%-88.9%).

Key words: ADDITION REACTION, ALPHA--SUBSTITUENT GROUP, PHOSPHONIC ACID ESTER, TRIMER, THIAZOLE P, PHOSPHOAMIDIC ACID P, CARBAMIDO GROUP, PHOSGENE, ISOCYANATE P, BENZOTHIAZOLE P