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Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (11): 1469-1471. Previous Articles     Next Articles

四齿四棱草根部的两个新二萜化合物

窦辉a,b, 彭树林a, 李帮经a, 罗水中c, 丁立生*,a   

  1. a中国科学院成都生物研究所 成都 610041;
    b浙江大学药学院中药与天然药物研究室 杭州 310031;
    c合肥工业大学生物工程系 合肥 230009
  • 收稿日期:2004-02-27 修回日期:2004-04-26 接受日期:2004-06-27 发布日期:2022-09-21
  • 通讯作者: * E-mail: lsding@cib.ac.cn

Two New Diterpenoids from the Roots of Schnabelia tetradonta

DOU Huia,b, PENG Shu-Lina, LI Bang-Jinga, LUO Shui-Zhongc, DING Li-Sheng*,a   

  1. aChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041;
    bDepartment of Traditional Chinese Medicine & Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031;
    cDepartment of Bioengineering, Hefei University of Technology, Hefei 230009
  • Received:2004-02-27 Revised:2004-04-26 Accepted:2004-06-27 Published:2022-09-21

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Two new 17(15→16)-abeo-20-nor-abietane diterpenoids, named schnabelolides A and B, were isolated from the ethanol extract of the roots of Schnabelia tetradonta (Lamiaceae), a Chinese endemic herb, through repeated column chromatographies. Their structures were elucidated as 17(15→16)-abeo-20-nor-abieta-12,16-epoxy-7,17-dihydroxy-5(10),6,8,12,15-pentaen-11,14-dion-18(1)-olide (1) and 17(15→16)-abeo-20-nor-abieta-12,16-epoxy-7-hydroxy-5(10),6,8,12,15-pentaen-11,14-dion-18(1)-olide (2) on the basis of spectroscopic evidence.

Key words: Schnabelia tetradonta, Lamiaceae, 17(15→16)-abeo-20-nor-abietane, schnabelolide A, schnabelolide B