Synthesis of New 4,5-Dihydro-2',5'-dioxo-pyrrolino[4,5-c]isoxazole Derivatives by 1,3-Dipolar Cycloaddition Reaction

Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (5): 521-524. Previous Articles Next Articles

1,3-偶极环加成合成新型4,5-二氢-2',5'-二氧杂吡咯啉并[4,5-c]异噁唑衍生物

刘方明^*,a, 邓莉平^b, 邬继荣^a, 文娜^b, 王厚勇^b

^a杭州师范学院化学系杭州 310012
^b新疆大学化学与化工学院乌鲁木齐 830046

收稿日期:2003-07-17 接受日期:2003-11-25 发布日期:2022-09-20
基金资助:
国家自然科学基金(Nos. 29702007, 20162004)资助项目.

Synthesis of New 4,5-Dihydro-2',5'-dioxo-pyrrolino[4,5-c]isoxazole Derivatives by 1,3-Dipolar Cycloaddition Reaction

LIU, Fang-Ming^*,a, DENG, Li-Ping^b, WU, Ji-Rong^a, WEN, Na^b, WANG, Hou-Yong^b

^aDepartment of Chemistry, Hangzhou Teachers College, Hangzhou 310012
^bCollege of Chemistry and Chemical Engineering, Xinjiang University, Ulumqi 830046

Received:2003-07-17 Accepted:2003-11-25 Published:2022-09-20
Contact: *E-mail: fmliu895@sohu.com

Abstract

Two series of new 4,5-dihydro-2',5'-dioxo-pyrrolino[4,5-c]isoxazoles have been synthesized by the reactionof N-arylmaleimides with nitrile oxide, prepared from 1,2,3-triazoly-4-hydroximoyl chloride and quinoxalinyl-2-hydroximoyl chloride in situ through 1,3-dipolar cycloaddition reaction. The structures of all new compounds were confirmed by elemental analysis, IR, ¹H NMR and MS spectral data.

Key words: quinoxaline, 1,2,3-triazole, pyrrolino[4,5-c]isoxazole, 1,3-dipolar cycloaddition

Cite this article

LIU, Fang-Ming, DENG, Li-Ping, WU, Ji-Rong, WEN, Na, WANG, Hou-Yong. Synthesis of New 4,5-Dihydro-2',5'-dioxo-pyrrolino[4,5-c]isoxazole Derivatives by 1,3-Dipolar Cycloaddition Reaction[J]. Chinese Journal of Organic Chemistry, 2004, 24(5): 521-524.

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1,3-偶极环加成合成新型4,5-二氢-2',5'-二氧杂吡咯啉并[4,5-c]异噁唑衍生物

Synthesis of New 4,5-Dihydro-2',5'-dioxo-pyrrolino[4,5-c]isoxazole Derivatives by 1,3-Dipolar Cycloaddition Reaction

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