Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (12): 1542-1547. Previous Articles     Next Articles

Review

硫化物的生物氧化成手性亚砜

姜标,黄浩,罗军,李祖义*   

  1. (中国科学院上海有机化学研究所 上海 200032)
  • 收稿日期:2005-06-01 修回日期:2005-09-30 发布日期:2005-11-30
  • 通讯作者: 李祖义

Chiral Sulfoxides by Biooxidation of Sulfides

JIANG Biao, LUO Jun, HUANG Hao, LI Zu-Yi*   

  1. (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032)
  • Received:2005-06-01 Revised:2005-09-30 Published:2005-11-30
  • Contact: LI Zu-Yi

This review was mainly focused on the catalytic asymmetric biooxidation of sulfides to chiral sulfoxides. Two enzymatic approaches in the oxidation of organic sulfides to optically active sulfoxides are described based on the use of chloroperoxidase and cyclohexanone monooxygenase.

Key words: chloroperoxidase, sulfoxides, cyclohexanone monooxygenase