Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (12): 1619-1625. Previous Articles    

Reports

光学活性脯氨酸催化的不对称有机合成反应

魏晓芳   

  1. (华东理工大学化学与制药学院 上海 200237)
  • 收稿日期:2005-02-01 修回日期:2005-08-15 发布日期:2005-11-30
  • 通讯作者: 魏晓芳

Optically Active Proline-catalyzed Enantioselective Organic Reactions

WEI Xiao-Fang   

  1. (Chemical and Pharmaceutical Institute, East China University of Science and Technology, Shanghai 200237)
  • Received:2005-02-01 Revised:2005-08-15 Published:2005-11-30
  • Contact: WEI Xiao-Fang

Optically active prolines, i.e., L-proline and D-proline, are efficient catalysts for enantioselective Aldol-type reactions of C=O, N=N, C=N or O=N bonds and enantioselective conjugate additions of α,β-unsaturated enones and 1-nitroalkenes to afford optically active organic molecules with polyfunctionality.

Key words: enantioselective catalysis, 1,2-addition, 1,4-addition, proline