Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (03): 337-340. Previous Articles     Next Articles

Original Articles

2-氰基-3-(2-氟吡啶-5-基)甲氨基-3-甲硫基氰基丙烯酸酯类化合物的合成及除草活性

邹小毛,郁丽敏,高颍,施欢乐,裴江,刘斌
李慧芬,胡方中,杨华铮*   

  1. (南开大学元素有机化学国家重点实验室 元素有机化学研究所 天津 300071)
  • 收稿日期:2005-01-30 修回日期:2005-09-28 发布日期:2006-02-28
  • 通讯作者: 杨华铮

Synthesis and Herbicidal Activity of 2-Cyano-3-(2-fluoropyrid-5-yl)- methylamino-3-methylthioacrylates

ZOU Xiao-Mao,YU Li-Min,GAO Yin,SHI Huan-Le,PEI Jiang,LIU Bin
LI Hui-Fen,HU Fang-Zhong,YANG Hua-Zheng*   

  1. (State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-organic Chemistry,
    Nankai University, Tianjin 300071)
  • Received:2005-01-30 Revised:2005-09-28 Published:2006-02-28
  • Contact: YANG Hua-Zheng

A series of 2-cyano-3-(2-fluoropyrid-5-yl)methylamino-3-methylthioacrylates were synthesized as herbicidal inhibitors of photosynthesis II electron transport and some of these compounds exhibited good herbicidal activities. A suitable group at the 3-position of acrylate is essential for high herbicidal activity. 2-Cyanoacrylates containing a 2-fluoro-5-pyridyl group may be provided higher herbicidal activities than relevant chloride derivatives.

Key words: herbicidal activity, SAR, 2-cyano-3-(2-fluoropyrid-5-yl)methylamino-3- methylthioacrylate, inhibitor of photosynthesis II electron transport