Henry Reaction of α-Ketoesters and α-Ketoamides

Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (9): 1291-1294. Previous Articles Next Articles

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α-酮酯和α-酮酰胺的Henry反应

王亚军，沈宗旋，张雅文*

(苏州大学化学化工学院江苏省有机合成重点实验室苏州 215006)

收稿日期:2005-10-17 修回日期:2006-01-11 发布日期:2006-09-11
通讯作者: 张雅文

Henry Reaction of α-Ketoesters and α-Ketoamides

WANG Ya-Jun,SHEN Zong-Xuan,ZHANG Ya-Wen*

(Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering,
Suzhou University, Suzhou 215006)

Received:2005-10-17 Revised:2006-01-11 Published:2006-09-11
Contact: ZHANG Ya-Wen

Abstract

The Henry reaction of cyclic α-ketoesters and α-ketoamides was achieved using triethylamine as a promoter. Twelve new multi-functional β-nitroalcohols were synthesized. Their structures were confirmed by elemental analyses, IR, ¹H NMR or ¹³C NMR spectroscopy. β-Nitroalcohols were produced in high yields under mild reaction conditions.

Key words: triethylamine, β-nitroalcohol, α-ketoester, α-ketoamide, Henry reaction

Cite this article

WANG Ya-Jun,SHEN Zong-Xuan,ZHANG Ya-Wen*. Henry Reaction of α-Ketoesters and α-Ketoamides[J]. Chin. J. Org. Chem., 2006, 26(9): 1291-1294.

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α-酮酯和α-酮酰胺的Henry反应

Henry Reaction of α-Ketoesters and α-Ketoamides

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