Synthesis and Biological Activities of Novel Oxime Ethers

Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (02): 228-234. Previous Articles Next Articles

Original Articles

一种结构新颖的肟醚类化合物的合成及其生物活性研究

吐松^a，徐龙鹤*^,a，于春睿^a，张弘^b，李志念^b

(^a大连理工大学精细化工国家重点实验室大连 116012)
(^b沈阳化工研究院沈阳 110021)

收稿日期:2006-04-24 修回日期:2006-05-30 发布日期:2007-01-30
通讯作者: 徐龙鹤

Synthesis and Biological Activities of Novel Oxime Ethers

TU Song^a, XU Long-He*^,a, YU Chun-Rui^a, ZHANG Hong^b, LI Zhi-Nian^b

(^aState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012)
(^bShenyang Research Institute of Chemical Industry, Shenyang 110021)

Received:2006-04-24 Revised:2006-05-30 Published:2007-01-30
Contact: XU Long-He

Abstract

Thirteen novel oxime ethers were designed and synthesized by modifying the side chain of oxime ether strobilurin fungicide with a benzopentatomic ring as the essential structure. Biological activity testing on these compounds showed that they all had good fungicidal activities against Eryiphe graminis and Pseudoperonospora cubensis. Indene-substituted compounds also had insecticidal activities. The key intermediate 2-acetylindene compounds were synthesized by one-pot palladium-catalyzed reaction in good yields.

Key words: strobilurin, 2-acetylindene, fungicidal activity, palladium-catalyzed, oxime ether

Cite this article

TU Song^a, XU Long-He*^,a, YU Chun-Rui^a, ZHANG Hong^b, LI Zhi-Nian^b. Synthesis and Biological Activities of Novel Oxime Ethers[J]. Chin. J. Org. Chem., 2007, 27(02): 228-234.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Penghui Li, Qingyang Xie, Fuxian Wan, Yuanhong Zhang, Lin Jiang. Synthesis and Fungicidal Activity of Novel Substituted Pyrimidine-5-carboxamides Bearing Cyclopropyl Moiety [J]. Chinese Journal of Organic Chemistry, 2024, 44(2): 650-656.
[2]	Min Liu, Dongyan Yang, Yumei Xiao, Wangcang Su, Fenghai Zhao, Qin Zhaohai .. Synthesis and Bioactivities of 5-Nitroimino-[1,4-2H]-1,2,4-triazolines as Olefin-Imidacloprid Mimics [J]. Chinese Journal of Organic Chemistry, 2023, 43(8): 2790-2799.
[3]	Huan Xu, Hongfei Wu, Xiaoming Zhang, Xingxing Lu, Tengda Sun, Yue Qi, Yufan Lin, Xinling Yang, Li Zhang, Yun Ling. Design, Synthesis and Bioactivity of Sulfonyl Hydrazides and Hydrazides Containing Fragment 1,2,3,4-Tetrahydroisoquinoline [J]. Chinese Journal of Organic Chemistry, 2023, 43(2): 725-733.
[4]	Changxing Sun, Fuhao Zhang, Huan Zhang, Penghui Li, Lin Jiang. Design, Synthesis, Fungicidal Activity and Molecular Docking Study of Novel 2-(1-Methyl-1H-pyrazol-4-yl)pyrimidine-4-carboxamides [J]. Chinese Journal of Organic Chemistry, 2023, 43(1): 229-235.
[5]	Lei Wang, Shujing Yu, Na Yang, Baolei Wang. Studies on the Synthesis and Biological Activities of Novel Dihydroquinazolinone-Containing Caffeine Derivatives [J]. Chinese Journal of Organic Chemistry, 2023, 43(1): 299-307.
[6]	Qian Zhang, Yihao Li, Leichuan Xu, Haoyun Ma, Xiangdong Li, Ming'an Wang. Synthesis and Fungicidal Activity of Novel Butenolide Compounds Containing Oxime Ether Moiety [J]. Chinese Journal of Organic Chemistry, 2022, 42(8): 2438-2448.
[7]	Changkai Wang, Tengda Sun, Xuebo Zhang, Xinling Yang, Xingxing Lu, Huan Xu, Fasheng Shi, Li Zhang, Yun Ling. Design, Synthesis and Bioactivity of Novel Fluoropyrazole Hydrazides [J]. Chinese Journal of Organic Chemistry, 2022, 42(5): 1527-1536.
[8]	Yang Han, Weichao Jiang, Jing Zhang, Jinsong Peng, Chunxia Chen. Visible-Light-Promoted Palladium-Catalyzed C—H Amination for the Synthesis of Carbazolequinones [J]. Chinese Journal of Organic Chemistry, 2022, 42(1): 266-276.
[9]	Weiwei Wang, Yihao Li, Xinlei Liu, Yu Zhao, Mingan Wang. Synthesis and Fungicidal Activity of Novel 3,7-Dimethylocta-2,6-dienamides and 3,7-Dimethyl-6,7-dihydroxyoct-2-enamides [J]. Chinese Journal of Organic Chemistry, 2021, 41(9): 3717-3725.
[10]	Can Jin, Xile Deng, Yong Zhou, Xiaomao Zhou. Design, Synthesis, Crystal Structure, and Fungicidal Activity of L-Carvone Derivatives Containing an Oxime Ester Moiety [J]. Chinese Journal of Organic Chemistry, 2021, 41(5): 2008-2018.
[11]	Hang Liu, Shuyun Zhang, Huan Li, Yan Zhang, Zhengming Li, Baolei Wang. Synthesis and Biological Activities of Novel 8-((3,4,4-Trifluorobut-3-en-1-yl)thio)-substituted Methylxanthines and Their Derivatives [J]. Chinese Journal of Organic Chemistry, 2021, 41(5): 2091-2098.
[12]	Honglei Jin, Fengxuan Jiang, Kai Cheng, Lehao Huang. Palladium-Catalyzed C8 Alkylation of 1-Naphthylamides and Its Application to the Synthesis of the Core Sturctures of Aporphine and Aristolactam Alkaloids [J]. Chinese Journal of Organic Chemistry, 2021, 41(4): 1691-1702.
[13]	Yuxun Zhao, Yunyun Wang, Chenglong Zhang, Xu Xu, Shifa Wang. Synthesis of Novel Camphor Sulfamoxime Ether Derivatives and Its Application in Antitumor Activity [J]. Chinese Journal of Organic Chemistry, 2021, 41(3): 1224-1233.
[14]	Wei Yu, Han Wang, Li-Jing Min, Xue-Wen Hua, Xing-Hai Liu. Synthesis and Fungicidal Activity of Novel Allyl Benzoate Compounds Containing Triazole [J]. Chinese Journal of Organic Chemistry, 2021, 41(2): 826-832.
[15]	Shuyun Zhang, Hang Liu, Lei Wang, Zhengming Li, Baolei Wang. Studies on the Synthesis, Structural Characterization and Biological Activities of Novel Caffeine Derivatives Containing Substituted-Piperazine Moiety [J]. Chinese Journal of Organic Chemistry, 2021, 41(10): 4075-4082.

一种结构新颖的肟醚类化合物的合成及其生物活性研究

Synthesis and Biological Activities of Novel Oxime Ethers

PDF

Knowledge

Cited

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments