Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (02): 272-275. Previous Articles     Next Articles

Reports

Pd(II)催化下苄基溴化锌或烯丙基碘化锌与芳香醛的加成反应

门秀琴,孟团结,王进贤*,辛丽   

  1. (西北师范大学化学化工学院 兰州 730070)
  • 收稿日期:2005-10-17 修回日期:2006-07-14 发布日期:2007-01-30
  • 通讯作者: 王进贤

Pd(II) Catalyzed Addtion Reaction of Benzylzinc Bromides or Allylzinc Iodines with Aromatic Aldehydes

MEN Xiu-Qin, MENG Tuan-Jie, WANG Jin-Xian*, XIN Li   

  1. (College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070)
  • Received:2005-10-17 Revised:2006-07-14 Published:2007-01-30
  • Contact: WANG Jin-Xian

The addition reaction of organozinc halides with aromatic aldehydes occurs readily catalyzed by amount [PdCl2(PPh3)2] to afford 1,2-addtion products in high yields. This method avoided the use of toxic CuCN/2LiCl and provided a simple way for the synthesis of aryl substituted secondary alcohols.

Key words: Pd(II) catalyzed, aromatic aldehyde, addition reaction, organozinc halide