Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (07): 819-829. Previous Articles     Next Articles

Review

不饱和烃杂钯化反应在有机合成中的应用

唐石,王乃兴*,李金恒*   

  1. (a湖南师范大学化学化工学院 化学生物学与中药分析教育部重点实验室 长沙 410081)
    (b中国科学院理化技术研究所 北京100101)
  • 收稿日期:2006-06-05 修回日期:1900-01-01 发布日期:2007-06-30
  • 通讯作者: 王乃兴*,李金恒*

Utilizations of Heteropalladation of Unsaturated Hydrocarbons in Organic Synthesis

TANG Shi,WANG Nai-Xing*,LI Jin-Heng*   

  1. (a Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education,
    College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081)
    (b Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101)
  • Received:2006-06-05 Revised:1900-01-01 Published:2007-06-30
  • Contact: WANG Nai-Xing*,LI Jin-Heng*

The heteropalladation reactions of unsaturated hydrocarbons are some of the most important routes to generate highly active alkylpalladium(II) and vinylpalladium(II) species. Under appropriate conditions, they can be trapped by some nucleophiles such as allylhalogens, carbon monoxide, unsaturated hydrocarbons, organoboric reagents and organostannic reagents etc. Followed by insertion and/or elimination to produce a variety of bioactive medicines, functional molecules and important building blocks. Recently, much attention has been attracted in the heteropalladation reactions. Here, recent advances in the heteropalladation reactions are reviewed.

Key words: aminopalladation, halopalladation, acetyloxypalladation, oxypalladation, heteropalladation