Recent Advances in the Stereoselective Synthesis of α-Cyanohydrins

Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (07): 1157-1163. Previous Articles Next Articles

Review

α-氰醇立体选择性合成新进展

耿晓红 ; 周辉 ; 陈沛然* ; 徐青

(东华大学化学化工与生物工程学院有机氟化学实验室上海 201620)

收稿日期:2007-07-02 修回日期:2007-09-24 发布日期:2008-07-28
通讯作者: 陈沛然*

Recent Advances in the Stereoselective Synthesis of α-Cyanohydrins

GENG, Xiao-Hong; ZHOU, Hui; CHEN, Pei-Ran* ; XU, Qing

(Laboratory of Organic Fluorine Chemistry, College of Chemistry, Chemical Engineering and Biotechnology,
Donghua University, Shanghai 201620)

Received:2007-07-02 Revised:2007-09-24 Published:2008-07-28
Contact: CHEN, Pei-Ran*

Abstract

Recent advances in the stereoselective synthesis of α-cyanohydrins are reviewed. The catalysts used in the synthesis included metal complex catalysts, organocatalysts and biocatalysts. Mechanistic details of some reactions are also introduced where available.

Key words: stereoselective synthesis, metal complex catalyst, hydrocyanation, cyanosilylation, organocatalysis, bio-catalyst, α-cyanohydrin

Cite this article

GENG, Xiao-Hong; ZHOU, Hui; CHEN, Pei-Ran* ; XU, Qing. Recent Advances in the Stereoselective Synthesis of α-Cyanohydrins[J]. Chin. J. Org. Chem., 2008, 28(07): 1157-1163.

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α-氰醇立体选择性合成新进展

Recent Advances in the Stereoselective Synthesis of α-Cyanohydrins

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