Progress in Reactions of 2(5H)-Furanone with Nucleophiles Containing Nitrogen

Chin. J. Org. Chem. ›› 2010, Vol. 30 ›› Issue (05): 648-654. Previous Articles Next Articles

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2(5H)-呋喃酮与含氮亲核试剂反应研究进展

宋秀美¹^{,2,3，李建晓¹，汪朝阳*^{,1，莫阳青¹}}

(¹华南师范大学化学与环境学院广州 510006)
(²广东高校新材料工程技术开发中心湛江 524048)
(³湛江师范学院化学系湛江 524048)

收稿日期:2009-07-27 修回日期:2009-09-03 发布日期:2009-11-03
通讯作者: 汪朝阳 E-mail:wangwangzhaoyang@tom.com
基金资助:
国家级.国家自然科学基金

Progress in Reactions of 2(5H)-Furanone with Nucleophiles Containing Nitrogen

Song Xiumei¹^{,2,3 Li Jianxiao¹ Wang Zhaoyang*^{,1 Mo Yangqing¹}}

(¹ Department of Chemistry, South China Normal University, Guangzhou 510006)
(¹Development Center for New Materials Engineering & Technology in Universities of Guangdong, Zhanjiang 524048)
(³ Department of Chemistry, Zhanjiang Normal College, Zhanjiang 524048)

Received:2009-07-27 Revised:2009-09-03 Published:2009-11-03
Contact: Zhaoyang Wang E-mail:wangwangzhaoyang@tom.com

Abstract

As a kind of α,β-unsaturated butyrolactone, 2(5H)-furanone is so reactive in lots of reactions that it has been used extensively in organic synthesis, especially, when a halogen atom is attached to the C＝C unsaturated bond. According to the different reaction points, the recent advance in reactions of 2(5H)-furanone with nucleophiles containing nitrogen to give cyclic derivatives with β-substituent, α,β-disubstituents or γ-substituent via Michael addition, tandem Michael addition-elimination, dipolar cycloaddition or palladium-catalyzed cross-coupling reactions is reviewed.

Key words: 2(5H)-furanone, nucleophile containing nitrogen, Michael addition, dipolar cycloaddition, tandem reaction

Cite this article

SONG Xiu-Mei, LI Jian-Xiao, WANG Chao-Yang, MO Yang-Qing. Progress in Reactions of 2(5H)-Furanone with Nucleophiles Containing Nitrogen[J]. Chin. J. Org. Chem., 2010, 30(05): 648-654.

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2(5H)-呋喃酮与含氮亲核试剂反应研究进展

Progress in Reactions of 2(5H)-Furanone with Nucleophiles Containing Nitrogen

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