Michael Addition of Methylene Active Compounds to Chalcones with Novel Task-specific Ionic Liquids as Catalysts under Solvent-free Conditions

Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (08): 1312-1318. Previous Articles Next Articles

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无溶剂条件下新型功能离子液体催化活性亚甲基化合物与查尔酮的Michael加成研究

应安国*，郑人华，武承林，梁华定，葛昌华，蒋华江

(台州学院医药化工学院台州 317000)

收稿日期:2010-11-20 修回日期:2011-02-16 发布日期:2011-03-28
通讯作者: 应安国 E-mail:yinganguo@163.com

Michael Addition of Methylene Active Compounds to Chalcones with Novel Task-specific Ionic Liquids as Catalysts under Solvent-free Conditions

YING An-Guo, ZHENG Ren-Hua, WU Cheng-Lin, LIANG Hua-Ding, GE Chang-Hua, JIANG Hua-Jiang

(School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 317000)

Received:2010-11-20 Revised:2011-02-16 Published:2011-03-28
Contact: An-Guo YING E-mail:yinganguo@163.com

Michael addition of methylene active compounds to chalcones using DBU (1,8-diazabicyclo- [5.4.0]undec-7-ene)-derived ionic liquids [DBU][Ac], [DBU][Lac], [DBU][Tfa], [DBU][n-Pr] and [DBU][n-Bu] as catalysts under solvent-free conditions was performed. The reactions proceed smoothly with high to excellent yields. The work-up is simple and the ionic liquid [DBU][Ac] could be reused six times without significant loss of catalytic activity.

Key words: DBU, task-specific ionic liquid, Michael addition, recycle

Cite this article

YING An-Guo, ZHENG Ren-Hua, WU Cheng-Lin, LIANG Hua-Ding, GE Chang-Hua, JIANG Hua-Jiang. Michael Addition of Methylene Active Compounds to Chalcones with Novel Task-specific Ionic Liquids as Catalysts under Solvent-free Conditions[J]. Chin. J. Org. Chem., 2011, 31(08): 1312-1318.

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无溶剂条件下新型功能离子液体催化活性亚甲基化合物与查尔酮的Michael加成研究

Michael Addition of Methylene Active Compounds to Chalcones with Novel Task-specific Ionic Liquids as Catalysts under Solvent-free Conditions

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