Chin. J. Org. Chem. ›› 2003, Vol. 23 ›› Issue (11): 1314-1316. Previous Articles     Next Articles

水中3-甲基-6-氨基-5-氰基-4-芳基-1-苯基-1,4-二氢吡喃[2,3-c]吡唑的洁净合成

史达清;张姝;庄启亚;屠树江;胡宏纹   

  1. 徐州师范大学化学系;南京大学化学系
  • 发布日期:2003-11-25

Clean Synthesis of 3-Methyl-6-amino-5-cyano-4-aryl-1-phenyl-1,4- dihydropyrano[2,3-c]pyrazole in Water

Shi Daqing;Zhang Shu;Zhang Qiya;Tu Shujiang;Hu Hongwen   

  1. Department of Chemistry, Xuzhou Normal University;Department of Chemistry, Nanjing University
  • Published:2003-11-25

The reaction of substituted arylmethylidenemalononitriles with 3- methyl-l-phenyl-2-pyrazolin-5-one in water in the presence of triethylbenzylainmonium chloride (TEBA) provides a fast, efficient and clean access to 3-methyl-6-amino-5-cyano-4-aryl-l-phenyl-l ,4- dihydropyrano[2,3-c]pyrazole.

Key words: TEBA, PROPANEDINITRILE P, PYRAZOLINE P, KETAL, PYRAZOLE P

CLC Number: